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99.9% Purity Raw Lenalidomide Pharmaceutical Intermediates CAS 191732-72-6

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99.9% Purity Raw Lenalidomide Pharmaceutical Intermediates CAS 191732-72-6

China 99.9% Purity Raw Lenalidomide Pharmaceutical Intermediates CAS 191732-72-6 supplier
99.9% Purity Raw Lenalidomide Pharmaceutical Intermediates CAS 191732-72-6 supplier 99.9% Purity Raw Lenalidomide Pharmaceutical Intermediates CAS 191732-72-6 supplier

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Product Details:

Place of Origin: China
Brand Name: Info@desen-nutrition.com
Certification: GMP,ISO9001,SGS,UKAS,FDA,CEC
Model Number: 191732-72-6

Payment & Shipping Terms:

Minimum Order Quantity: Free samples Available
Price: Negotiation
Packaging Details: As requires
Delivery Time: 4-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: Mass in stock
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Detailed Product Description
Name: Lenalidomide CAS: 191732-72-6
MF: C13H13N3O3 MW: 259.2606
Appearance: White Crystalline Powder Packing: Discreet Packing For Customs Pass Guaranteed
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raw pharmaceutical materials

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raw materials for pharmaceutical products

Lenalidomide (Revlimid) is an immunomodulatory drug that is a more potent analog of thalidomide and is approved in multiple myeloma and transfusion-dependent myelodysplasia. It has clinical activity in a variety of other malignancies, including CLL.
 
Two initial studies examining either an intermittent 25-mg daily oral dose for 21 days or a 5-mg daily oral dose with dose escalation to a 10-mg daily oral dose as tolerated given as continuous therapy were pursued initially in patients with relapsed CLL. The higher-dose, intermittent schedule was active with an ORR of 47% and a 9% CR. Major side effects of this therapy were cytopenias, rash, and tumor flare, which in some cases can be life threatening.
 
99.9% Purity Raw Lenalidomide Pharmaceutical Intermediates CAS 191732-72-6
 
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Name:  Lenalidomide
Synonyms: 3-(7-amino-3-oxo-1h-isoindol-2-yl)piperidine-2,6-dione; 1-Oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline; 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; CC-5013; Revlimi; Lenalidomide(other anti-cancers); 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
MF: C13H13N3O3
MW: 259.2606
CAS: 191732-72-6
Molecular Structure:
99.9% Purity Raw Lenalidomide Pharmaceutical Intermediates CAS 191732-72-6
 
Descriptions:
 
Lenalidomide (trade name Revlimid) is a derivative of thalidomide introduced in 2004.
 
Lenalidomide was initially intended as a treatment for multiple myeloma, for which thalidomide is an accepted therapeutic treatment. Lenalidomide has also shown efficacy in the class of hematological disorders known as myelodysplastic syndromes (MDS). Along with several other drugs developed in recent years, lenalidomide has significantly improved overall survival in myeloma (which formerly carried a poor prognosis), although toxicity remains an issue for users.
 
Medical uses:
 
Multiple myeloma
 
Multiple myeloma is a cancer of the blood, characterized by accumulation of a plasma cell clone in the bone marrow. Lenalidomide is one of the novel drug agents used to treat multiple myeloma. It is a more potent molecular analog of thalidomide, which inhibits tumor angiogenesis, tumor secreted cytokines and tumor proliferation through the induction of apoptosis.
 
Compared to placebo, lenalidomide is effective at inducing a complete or "very good partial" response as well as improving progression-free survival. Adverse events more common in people receiving lenalidomide for myeloma were neutropenia (a decrease in the white blood cell count), deep vein thrombosis, infections, and an increased risk of other hematological malignancies. The risk of second primary hematological malignancies does not outweigh the benefit of using lenalidomide in relapsed or refractory multiple myeloma. It may be more difficult to mobilize stem cells for autograft in people who have received lenalidomide.
 
Myelodysplastic syndromes
 
With myelodysplastic syndromes, the best results of lenalidomide were obtained in patients with the Chromosome 5q deletion syndrome (5q- syndrome). The syndrome results from deletions in human chromosome 5 that remove three adjacent genes, granulocyte-macrophage colony-stimulating factor, Platelet-derived growth factor receptor B, and Colony stimulating factor 1 receptor.
 
Other cancers
 
Lenalidomide is undergoing clinical trial as a treatment for Hodgkin's lymphoma, as well as non-Hodgkin's lymphoma, chronic lymphocytic leukemia and solid tumor cancers, such as carcinoma of the pancreas. One Phase 3 clinical trial being conducted by Celgene in elderly patients with B-cell chronic lymphocytic leukemia was halted in July 2013 when a disproportionate number of cancer deaths were observed during treatment with lenalidomide versus patients treated with chlorambucil.
 
Packaging & Shipping:
 
Packing: 1kg/bag; 25kg/drum
Shipping: By Courier, Air and sea
 
Metolazone CAS 17560-51-9 Medicine Grade 99% Purity Metolazone For Treating Oedema
FAQ --- Order Guides:
 
Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Xiaogan, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
 
Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.
 
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
 
Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service
 
Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!
 
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal.
 
Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.
 
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