Payment & Shipping Terms:
|Whatsapp:||86-18908446193||Packing:||Discreet Packing For Customs Pass Guaranteed|
|Alias:||YK11||Category:||Selective Androgen Receptor Modulator|
home brewing testosterone,
raw hormone powders
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells.
Androgen Receptor Modulator Powder YK11 Sarm Steroids CAS 431579-34-9
What is YK11?
(17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel androgen receptor (AR) partial agonist. as well as by dihydrotestosterone (DHT).
The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products.
YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won’t have androgenic side affects like hair loss, acne, etc.
The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties ofYK11.
How YK11 works?
Most SARMS have quite limited androgenic side effects, but frequently only quite few anabolic effects when likened to testosterone. But, this doesn’t occur for YK11 as reported in Biological and Pharmaceutical Bulletin in 2013.
YK11 attaches itself to the AR (androgen receptor), but only inducts methods that lead to the traditional side effects of androgens such as growth of body hair and prostate and enhanced aggression – to a restricted degree.
YK11 induces muscle cells to make more follistatin (more than DHT does) – a strong myostatin inhibitor.
YK11 works through the androgen receptor.
Kanno tested C2C12 muscle cells and not lab animals or humans. It has been discovered that muscle cells produce more anabolic factors if exposed to 500 nmol (nanomoles) YK11 than if you expose the same muscle cells to 500 nmol DHT.
With that said, YK11 can be as good as testosterone in terms of muscle strengthening, but minus the detrimental side effects.
YK11 Dosages and Suggestion:
Recommended maximum dose YK11 is require dosages of 2.0-5.0mg b.i.d. in males and 0.5mg-2mg b.i.d. in females to achieve optimal effects in humans for the noted indications.
SARMS We offer:
|AICAR||2627-69-2||acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown|
|MK2866||841205-47-8||medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy.|
|MK-677||15972-10-0||A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly|
|LGD-4033||1165910-22-4||pharmacological profile similar to that of enobosarm, Ostarine,MK-2866|
|GW501516||317318-70-0||For obesity, diabetes, dyslipidemia and cardiovascular disease|
|Andarine(S4)||401900-40-0||partial agonist, intended mainly for treatment of benign prostatic hypertrophy|
|SR9009||1379686-30-2||under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice|
|SR9011||1379686-30-2||For obesity, diabetes, dyslipidemia and cardiovascular disease|
|RAD140||1182367-47-0||New generation for gaining mass and cutting edges|
|a SARM and myostatin inhibitor in one|
|GHRP-2||158861-67-7||Growth Hormone Releasing Peptide-2|
|GHRP-6||87616-84-0||Growth Hormone Releasing Peptide-6|
|TB500||107761-42-2||Thymosin beta 4|
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
5. Service: Best Service with after-sales service and consultation.
We can offer professional design lables and suggestions for your own Steroids Brands !
Professional Laboratory with Advanced Equipments & Developed Technology , Pre-finished Steroid Oil, Customized Concentration Available! ( HOT: Test E 300, Anavar 50, Sus 250, Deca 250, Dbol 50, Winstrol 50, Tren E 200, BU 300, Mast P 100, Primo 100, NPP 200, Tren Hex 50, Tritren 180, Anomass 400, Test Blend 450, Supertest 450)
If you are going to start your own business with any new brand names, come to us !
1. Professional lab technical guidance (For finished gears producers or lab owners)
2. Equipment and Machines Support (Filtering machine , Caps ,bottles and crimper )
3. Label designing and printing Assistance ( Customize box and label )
Contact Person: Sales Manager