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CAS 218949-48-5 High Purity Human Growth Peptides Tesamorelin Lyophilized Powder for Muscle Building

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CAS 218949-48-5 High Purity Human Growth Peptides Tesamorelin Lyophilized Powder for Muscle Building

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Large Image :  CAS 218949-48-5 High Purity Human Growth Peptides Tesamorelin Lyophilized Powder for Muscle Building

Product Details:
Place of Origin: China
Brand Name: ChineseHormone
Certification: ISO9001,SGS,UKAS
Model Number: CAS:218949-48-5
Payment & Shipping Terms:
Minimum Order Quantity: Free samples Available
Price: Negotiable
Packaging Details: Discreet package or as required
Delivery Time: 3-6 working days
Payment Terms: T/T, Western Union, MoneyGram,BItcoins
Supply Ability: 500 kg / month
Detailed Product Description
Assay: 99% Character: White Powder
Grade: Pharmaceutical Grade Packing: Discreet Ways Of Packing For Customs Pass Guaranteed
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CAS 218949-48-5 High Purity Tesamorelin / Peptides Lyophilized Powder for Muscle Building

 

Product Name:Tesamorelin (2mg/vial)
CAS:218949-48-5
MF:C211H366N72O67S1
MW:5135.89
Purity(HPLC):99.00%min

Specification: 2mg/vial
Appearance: White Lyophilized Powder
Method of Analysis: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.
Packing: Discreet package or as required.
 
Product Name: Tesamorelin Other Names: GHRF MF: C221H366N72O67S
EINECS No.: N/A Type: Immune Function Agents, Vitamins, Amino Acids and Coenzymes Type: Immune Function Agents, Vitamins, Amino Acids and Coenzymes
Grade Standard: Medicine Grade Usage: Animal Pharmaceuticals Dry: Freeze
CAS No.: 901758-09-6 Purity: 98%min, 99%    
Molecular Formula: C221H366N72O67S Appearance: White powder    
Assay: HPLC 99% Package`: 10 mg/vial    

 

Description:

 

Tesamorelin is a synthetic form of growth-hormone-releasing hormone (GHRH) which is used in the treatment of HIV-associated lipodystrophy.It is a synthetic peptide consisting of all 44 amino acids of human GHRH with the addition of a trans-3-hexenoic acid group.

 

Tesamorelin, (formerly known as TH9507), is a type of peptide called a growth hormone-releasing factor (GHRF). GHRF causes growth hormone to be created and spread in the body, which helps increase metabolism, reduce belly fat, improve body shape, and use of energy. Tesamorelin (formerly known as TH9507) is a synthetic growth hormone-releasing factor that stimulates the pituitary gland in the brain to secrete growth hormone; this indirect approach appears to maintain more stable, natural levels, like CJC-1295 DAC,. Clinical trials have shown that tesamorelin significantly reduces abdominal fat with fewer side effects than human growth hormone itself, although abdominal fat may return after the Tesamorlein is discontinued (depending upon the individual). Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals as well as similarly reducing abdominal fat in NON-HIV-Infected individuals.

 

CAS 218949-48-5
SYNONYMS Hex-hGRF, ThGRF(1-44), TH-9507, (Hexenoyl trans-3)-hGRF(1-44)-NH2
SEQUENCE trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
CHEMICAL NAME NA
MOLECULAR FORMULA C221H366N72O67S
MOLECULAR WEIGHT 5135.77794
PURITY ≥98% (HPLC)
PHYSICAL STATE Lyophilized Powder
SOLUBILITY Soluble in water or 1% acetic acid
STORAGE Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.

 

Usage:


Tesamorelin is a stabilized analogue of the growth hormone-releasing factor (GRF) that induces growth hormone (GH) in a specific and physiological manner. To date, clinical studies suggest that Tesamorelin reduces visceral fat in HIV-infected patients with abdominal lipo-hypertrophy as well as reducing abdominal fat in all individuals studied.

A peptide that increases growth hormone release improved several measures of cognitive function in cognitively normal and mildly impaired older individuals in a placebo-controlled trial, a researcher said here. Scores on standard tests of executive function and verbal memory were significantly higher in participants given tesamorelin (Egrifta), a synthetic analog of growth hormone releasing hormone (GHRH), in a 20-week trial, according to Laura D. Baker, PhD.. Participants taking the drug in the 78-person trial also reported greater subjective improvement in cognition relative to the placebo group.

In animal studies, GHRH administration improved biomarkers of brain function as well as performance on cognition tests. And a 2006 clinical trial with GHRH found small but significant improvements in cognitive test scores in healthy older adults. In the current study, funded by the National Institute on Aging, 41 cognitively normal adults and 37 with mild cognitive impairment were randomized to placebo or tesamorelin at 1 mg/day subcutaneously.

Mean participant age was 66 to 70 among the four groups. Scores on the Mini-Mental State Examination averaged 29 for the normal participants and 28 for those with mild impairments. Normal and impaired participants differed more at baseline on a test of story recall, with mean scores of 54 and 44, respectively. Tesamorelin appeared to have a protective effect relative to placebo among the cognitively impaired patients on this measure. At the final evaluation, scores declined an average of five points with placebo, whereas those assigned to tesamorelin had a mean decline of less than one point.

Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals. Lipodystrophy is a condition that causes changes in placement of body fat, including wasting and fat accumulation, and changes in metabolism. Similar to Tesamorelin is Sermorelin, which may be taken with GHRP-6 is clinical trials. Individuals with lipodystrophy may develop excess fat most notably around the liver, stomach, and other abdominal organs (visceral body fat).

 

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