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CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS

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CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS

China CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS supplier
CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS supplier CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS supplier CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS supplier CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS supplier

Large Image :  CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS

Product Details:

Place of Origin: China
Brand Name: ChineseHormone
Certification: ISO9001,SGS,UKAS
Model Number: 23454-33-3

Payment & Shipping Terms:

Minimum Order Quantity: Free sample available
Price: Negotiable
Packaging Details: Discreet package or as required
Delivery Time: 3-6 working days
Payment Terms: T/T, Western Union, MoneyGram, Bitcoins
Supply Ability: 500 kg / month
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Detailed Product Description
Product Name: Dexamethasone Purity: 99%
MF: C22H29FO5 MW: 392.46
Appearance: White Powder Packing: Discreet Packing For Customs Pass Guaranteed
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Pharmaceutical Intermediates Anti-inflammatory Dexamethasone (DXMS) CAS 23454-33-3

 

Dexamethasone (DXMS) Quick Details:

 

Product name: Dexamethasone
CAS: 50-02-2
MF: C22H29FO5
MW: 392.46
EINECS: 200-003-9
Standard: EP
Content: 99%
Chemical properties: white or white crystalline powder; odorless. 
Category: pharmaceutical raw materials
Field: antiallergic drugs
Extension products: Dexamethasone Tablets
Application: Mainly anti-inflammatory, antivirus, allergy, anti-rheumatism, clinical is used more widely. 

 

CAS 23454-33-3 Pharmaceutical Intermediates Anti-inflammatory Dexamethasone DXMS

 

Dexamethasone Description:


Dexamethasone is a type of corticosteroid medication. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis. In adrenocortical insufficiency, it should be used together with a medication that has greater mineralocorticoid effects such as fludrocortisone. In preterm labor, it may be used to improve outcomes in the baby. It may be taken by mouth, as an injection into a muscle, or intravenously. The effects of dexamethasone are frequently seen within a day and last for about three days.


Medical Uses:


1, Anti-inflammatory

 

Dexamethasone is used to treat many inflammatory and autoimmune conditions, such as rheumatoid arthritis and bronchospasm. Idiopathic thrombocytopenic purpura, a decrease in numbers of platelets due to an immune problem, responds to 40 mg daily for four days; it may be administered in 14-day cycles. It is unclear whether dexamethasone in this condition is significantly better than other glucocorticoids.

 

2, Cancer

 

People with cancer undergoing chemotherapy are often given dexamethasone to counteract certain side effects of their antitumor treatments. Dexamethasone can increase the antiemetic effect of 5-HT3 receptor antagonists, such as ondansetron. The exact mechanism of this interaction is not well-defined, but it has been theorized that this effect may be due to, among many other causes, inhibition of prostaglandin synthesis, anti-inflammatory effects, immunosuppressive effects, decreased release of endogenous opioids, or a combination of the aforementioned.

 

Dexamethasone is also used as a direct chemotherapeutic agent in certain haematological malignancies, especially in the treatment of multiple myeloma, in which dexamethasone is given alone or in combination with other chemotherapeutic drugs, including most commonly with thalidomide (Thal-dex), lenalidomide, bortezomib (Velcade, Vel-dex), or a combination of doxorubicin (Adriamycin) and vincristine or bortezomib/lenalidomide/dexamethasone.

 

3, Endocrine

 

Dexamethasone is the treatment for the very rare disorder of glucocorticoid resistance.

In adrenal insufficiency and Addison's disease, dexamethasone is prescribed when the patient does not respond well to prednisone or methylprednisolone.

 

It can be used in congenital adrenal hyperplasia in older adolescents and adults to suppress ACTH production. It is typically given at night.

 

4, Pregnancy

 

Dexamethasone may be given to women at risk of delivering prematurely to promote maturation of the fetus' lungs. This has been associated with low birth weight, although not with increased rates of neonatal death.

 

Dexamethasone has also been used during pregnancy as an off-label prenatal treatment for the symptoms of congenital adrenal hyperplasia (CAH) in female fetuses. CAH causes a variety of physical abnormalities, notably ambiguous genitalia in girls. Early prenatal CAH treatment has been shown to reduce some CAH symptoms, but it does not treat the underlying congenital disorder. This use is controversial: it is inadequately studied, only around one in ten of the foetuses of women treated are at risk of the condition, and serious adverse events have been documented.

 

5, High-altitude illnesses

 

Dexamethasone is used in the treatment of high-altitude cerebral edema (HACE), as well as high-altitude pulmonary edema (HAPE). It is commonly carried on mountain-climbing expeditions to help climbers deal with complications of altitude sickness.

 

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