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CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator

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CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator

China CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator supplier
CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator supplier CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator supplier CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator supplier CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator supplier

Large Image :  CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator

Product Details:

Place of Origin: China
Brand Name: ChineseHormone
Certification: ISO9001,SGS,UKAS,GMP
Model Number: CAS 89778-27-8

Payment & Shipping Terms:

Minimum Order Quantity: Free samples Available
Price: Negotiable
Packaging Details: Discreet package or as required
Delivery Time: 2-5 working days
Payment Terms: Western Union, MoneyGram, T/T,Bitcoins
Supply Ability: 5000 kg / month
Contact Now
Detailed Product Description
Email: Aaron@desen-nutrition.com Packing: Discreet Packing For Customs Pass Guaranteed
Assay: 99% CAS: 89778-27-8
MF: C26H28ClNO・C6H8O7 MW: 598.09
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CAS: 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment Assay 99%

 

Toremifene Citrate Quick Details:

 

Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. Toremifene citrate is also being evaluated for prevention of prostate cancer under the brand name Acapodene.

 

Product Name Toremifene citrate
Molecular Formula C26H28ClNO・C6H8O7
Molecular Weight 598.09
CAS 89778-27-8
Molecular Structure CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator
Appearance White Crystalline Powder

 

Toremifene Citrate Descriptions:

 

In 2007 the pharmaceutical company GTx, Inc was conducting two different phase 3 clinical trials; First, a pivotal Phase clinical trial for the treatment of serious side effects of androgen deprivation therapy (ADT) (especially vertebral/spine fractures and hot flashes, lipid profile, and gynecomastia) for advanced prostate cancer, and second, a pivotal Phase III clinical trial for the prevention of prostate cancer in high risk men with high grade prostatic intraepithelial neoplasia, or PIN. Results of these trials are expected by first quarter of 2008.

 

An NDA for the first application (relief of prostate cancer ADT side effects) was submitted in Feb 2009, and in Oct 2009 the FDA said they would need more clinical data, e.g. another phase III trial.

 

Toremifene Citrate COA:

 

TEST ITEMS SPECIFICATION RESULTS
Description White or Almost White Crystalline Powder White Powder
Identification Positive Positive
Assay 97.00~103.00% 99.38%
Loss On Drying 0.5%max 0.25%
Melting Point 95~99¡ãC 96.0~98.0¡ãC
Specific Rotation +48¡ã~+51¡ã +49.0¡ã
Organic Volatile Impurities meets the requirments. Conforms
Residual Solvents meets the requirments. Conforms
Conclusion The specification conform with USP32 standard

 

Toremifene Citrate Applications:

 

It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there.

 

Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.

 

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Can be used as pharmaceutical material

 

CAS 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator

Shipping:


1. Preferentially DHL or HKEMS for quantity less than 50KG;
2. Sea shipping for quantity over 60KG. 100% safe!
3. Send from our agent in Singapore, Laos, Netherlands.

 

We provide re-ship policy, So there are not any loss once you order from us and I guarantee delivery and your interests!

 

FAQ:

 

Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Xiaogan, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.

 

Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.

 

Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.

 

Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service

 

Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!

 

Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal.

 

Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.

 

 

Contact Details
Hengyang Desen Biotechnology Co., Ltd.

Contact Person: Aaron

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