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DSIP Delta Sleep Inducing Peptide 62568-57-4 narcolepsy Polypeptide MDD anticarcinogenic

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DSIP Delta Sleep Inducing Peptide 62568-57-4 narcolepsy Polypeptide MDD anticarcinogenic

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Large Image :  DSIP Delta Sleep Inducing Peptide 62568-57-4 narcolepsy Polypeptide MDD anticarcinogenic

Product Details:
Place of Origin: China
Brand Name: ChineseHormone
Certification: ISO9001,SGS,UKAS
Model Number: CAS:62568-57-4
Payment & Shipping Terms:
Minimum Order Quantity: Free samples Available
Price: Negotiable
Packaging Details: Discreet package or as required
Delivery Time: 3-6 working days
Payment Terms: T/T, Western Union, MoneyGram,BItcoins
Supply Ability: 500 kg / month
Detailed Product Description
Assay: 99% Character: White Lyophilized Powder
Grade: Pharmaceutical Grade Packing: Discreet Ways Of Packing For Customs Pass Guaranteed
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DSIP Delta Sleep Inducing Peptide 62568-57-4 narcolepsy Polypeptide MDD anticarcinogenic

 

Product Name:DSIP (2mg/vial)
Alias:Delta Sleep Inducing Peptide;DSIP nonapeptide;Emideltide
CAS:62568-57-4
MF:C35H48N10O15
MW:848.81
Purity:99%
Appearance:White Lyophilized Powder
Standard:USP
Certification:SGS
Method of Analysis:HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.

 
Product Name: DSIP
Synonyms: SLEEP INDUCING PEPTIDE;WAGGDASGE;TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O;DELTA SLEEP INDUCING PEPTIDE;DELTA SLEEP-INDUCING PEPTIDE 4H2O;DSIP
CAS: 62568-57-4
MF: C35H48N10O15
MW: 848.81
Product Categories: Peptide
Mol File: 62568-57-4.mol
DSIP Structure

 

Usage:

 

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.


It have anticarcinogenic properties and have geroprotective effects.In addition,it can be used to treat major depressive disorder (MDD).

 

Description:

 

Delta sleep-inducing peptide was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.

 

DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif.It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

 

Applications:

 

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.

Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies.

 

Function:

 

Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies.

 

Decreases basal corticotropin level and blocks its release.

 

Stimulates release of luteinizing hormone (LH).

 

Stimulates release of somatoliberin and somatotrophin secretion and inhibits somatostatinsecretion.

Can act as a stress limiting factor.

 

May have a direct or indirect effect on body temperature and alleviating hypothermia.

Can normalize blood pressure and myocardial contraction.

 

It has been shown to enhance the efficiency of oxidative phosphorylation in rat mitochondria in vitro, suggesting it may haveantioxidant effects.

 

There is also conflicting evidence as to its involvement in sleep patterns. Some studies suggest a link between DSIP and slow-wave sleep (SWS) promotion and suppression of paradoxical sleep, while some studies show no correlation. Stronger effects on sleep have been noted for the synthesized analogues of DSIP.

 

It may have an impact on human lens epithelial cell function via the MAPK pathway, which is involved in cell proliferation, differentiation, motility, survival, and apoptosis.

 

It has been found to have anticarcinogenic properties. In a study on mice, injecting a preparation of DSIP over the mice's lifetime decreased total spontaneous tumor incidence 2.6-fold.

 

The same study found it to also have geroprotective effects: it slowed down the age-related switching-off of oestrous function; it decreased by 22.6% the frequency of chromosome aberrations inbone marrow cells and it increased by 24.1% maximum life span in comparison with the control group.

 

Specifications:

 


Product Name
DSIP
CAS 62568-57-4
standard ISO9001, GMP
Purity 99%min
Appearance White Lyophilized Powder
Package as required
Minimum order quantity 10g
passment Professional team special for package and shipment and staring on tracking
  code 24hours for customs pass guaranteed
Shipping leading time Within 24 hours after receiving the payment
Payment options Western Union, MoneyGram, T/T,Bank transfer
Shipping 1)Express delivery with DHL,EMS,Fedex,HKEMS,TNT,UPS
  (Express delivery within 24 hours after payment)
  2)By sea (large quantity ,it will take 30-45days)
Price Negotiated
Supply ability 100000 vials/month

 

Contact Details
Hengyang Desen Biotechnology Co., Ltd.

Contact Person: Sales Manager

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