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DXM / Dextromethorphan hydrobromide Antitussive Drug CAS 125-69-9

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DXM / Dextromethorphan hydrobromide Antitussive Drug CAS 125-69-9

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Large Image :  DXM / Dextromethorphan hydrobromide Antitussive Drug CAS 125-69-9

Product Details:
Place of Origin: China
Brand Name: ChineseHormone
Certification: GMP, ISO 9001, USP
Model Number: CAS 125-69-9
Payment & Shipping Terms:
Minimum Order Quantity: Free samples Available
Price: negotiated
Packaging Details: as your required
Delivery Time: 3-7 working days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 500-1000 kg / month
Detailed Product Description
MW: 352.31 MF: C18H26BrNO
Appearance: White Crystalline Powder Water Solubility: 40 MM In Water
Alias: DXM,dextromethorphan HBr Shipment:: FedEx, TNT, EMS, DHL.UPS,EUB
High Light:

raw pharmaceutical materials

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raw materials for pharmaceutical products

 

DXM / Dextromethorphan hydrobromide Antitussive Drug CAS 125-69-9

 

Dextromethorphan (DXM) is an antitussive (cough suppressant) drug. It is one of the active ingredients in many over-the-counter cold and cough medicines. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications.

 

Usage:

 

DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonis

 

This medication is used for temporary relief of coughs without phlegm that are caused by certain infections of the air passages (e.g., sinusitis, common cold). This product should not usually be used for an ongoing cough from smoking or long-term breathing problems (e.g., chronic bronchitis, emphysema) unless directed by your doctor. This product contains dextromethorphan. It is a cough suppressant that works by decreasing the feeling of needing to cough.

 

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Ask your doctor or pharmacist for more details about using your product safely.

 

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

 

Product name
Dextromethorphan Hydrobromide
CAS No.
125-69-9
Outer Packing
25KG /drum
Production date
2016.08.11
Shelf life
2020.08.10
Standard adopted
USP38/EP8
Items of analysis
Specification
Results
Apperance
Practically white crystal or crystalline powder
White crystalline powder
FT-IR
The sample spectrum correspond to that of the reference standard
Conforms
UV
Not more than 3.0% difference of RS(on anhydrous basis)
2.7%
Bromide Test
Yellow white precipitate forme
Conforms
Specific rotation A
1.8w/v in water:Not more than 1.0%difference of RS
0.4%
Specific rotation B
2.0%w/v in 0.1M HCL: +28℃to +30℃ at 589nm and 20℃(on anhydrous basis)
+28.4℃
Clarity of solution
5.0%w/v in alcohol:Clear and colorless
Conforms
PH
5.2-6.5(1 in 100 water solution)
5.7
Acidity or Alkalinity
Not more than 0.4ml of 0.01M HCLconsumed
0.30ml
Water(by KF Titration)
4.0%—5.5%
4.9%
impurities A,B,C,D
For each of impurities A,B,C,D not more than 0.5%
Impurities A,B,C,D; Not detected.
impurities A,B,C,D
Among impurities A,B,C,D not more than one greater than 0.25%
0
For each of unspecified impurities
not more than0.10%
﹤0.05%
Total impurities
not more than 1.0%
﹤0.05%
Residue on Ignition
Not more than 0.1%
0.08%
N,N-Dimethylaniline
Not more than 0.001%
Conforms
Phenolic compounds
No blue-green color develops
Conforms
Assay A (by HPLC)
98.0%~102.0%(on anhydrous basis)
99.9%
Assay B(by titration)
99.0%~101.0%(on anhydrous basis)
99.2%
Methanol
≤3000ppm
N.D
Toluene
≤890ppm
5.8ppm
Acetone
≤5000ppm
Conforms
Storage
Preserve in tight containers;protected from light
Conforms
Conclusion
Qualified

 

DXM / Dextromethorphan hydrobromide Antitussive Drug CAS  125-69-9 0

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