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Dextromethorphan Hydrobromide is used for temporary relief of coughs without phlegm that are caused by certain infections of the air passages (e.g., sinusitis, common cold). Dextromethorphan Hydrobromide should not usually be used for an ongoing cough from smoking or long-term breathing problems (e.g., chronic bronchitis, emphysema) unless directed by your doctor. Dextromethorphan Hydrobromide contains dextromethorphan. It is a cough suppressant that works by decreasing the feeling of needing to cough.
DXM Natural Oral Dextromethorphan Hydrobromide For Temporary Relief Of Coughs CAS 125-69-9
1. Dextromethorphan Hydrobromide Quick Detail:
Product Name: Dextromethorphan Hydrobromide
CAS Number: 125-69-9
Molecular Weight: 352.3091
Synonyms: Dextromethorphan Hydrobromide; Dextromethorphan HBr
Boiling Point: 427.5 C at 760 mmHg
Flash Point: 212.3 C
Appearance: White crystalline powder
Application: The central Antitussives mainly inhibit the extension of the brain's cough center and play
a role, used for treatment of little phlegm cough caused by colds, acute and chronic bronchitis, sore
throat, bronchial asthma, tuberculosis and other upper respiratory tract infections.
2. Dextromethorphan Hydrobromide COA:
|Test Items||Specification||Test Results|
|Appearance||white or almost white crystalline powder, slightly smelly||white crystalline powder|
|Residue On Ignition||Not more than 0.1%||Conforms|
|N.N - dimethylaniline||Comply with the standard||Conforms|
|Phenolic Compounds||Comply with the standard||Conforms|
|Related Substance||Comply with the standard||Conforms|
This batch is complies with USP 34.
3. Dextromethorphan Hydrobromide Applications:
Dextromethorphan Hydrobromide is also used recreationally. When exceeding label-specified maximum dosages, Dextromethorphans acts as a dissociative hallucinogen.
Dextromethorphan Hydrobromide 's mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist.
In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic such as ketamines and phencyclidine. As well, the metabolite 3-methoxymorphinans of dextrorphan (thus a second-level metabolite of DXMs) produces local anesthetic effects in rats with potency above dextrorphan, but below that of Dextromethorphan Hydrobromide.
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