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Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism

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Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism

China Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism supplier
Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism supplier Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism supplier Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism supplier

Large Image :  Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism

Product Details:

Place of Origin: China
Brand Name: ChineseHormone
Certification: GMP, ISO 9001, USP
Model Number: CAS 57-63-6

Payment & Shipping Terms:

Minimum Order Quantity: Free samples Available
Price: negotiated
Packaging Details: as your required
Delivery Time: 3-7 working days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 500-1000 kg / month
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Detailed Product Description
MF: C20H24O2 MW: 296.403
Appearance: White To Creamy White Crystalline Powder Biological Half-life: 7–36 Hours
Chemical Name: (17α)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17β-diol Bioavailability :: 38–48%
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Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism

 

CAS Number 57-63-6

Formula:C20H24O2

Molar mass :296.403 g/mol

Biological half-life :7–36 hours

Bioavailability :38–48%

Chemical Structure:

Ethinyl Estradiol Raw Steroid Powders for the Treatment of Female Hypogonadism

Synonyms :(17α)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17β-diol

 

Ethinyl estradiol (EE) (USP) (former brand name Estinyl), or ethinylestradiol (INN, USAN, JAN), also spelled as ethinylœstradiol (BAN) and also known as 17α-ethynylestra-1,3,5(10)-triene-3,17β-diol, is a synthetic, steroidal estrogen. It is a derivative of estradiol, the major endogenous estrogen in humans; specifically, EE is 17α-ethynylestradiol. EE is an orally active estrogen used in almost all formulations of combined oral contraceptives (COCs), being nearly the exclusive estrogen used for this purpose.

 

Medical uses

 

As Estinyl, EE was formerly used for hormone replacement therapy in menopause and the treatment of female hypogonadism, loss of menstruation, dysmenorrhea, acne, prostate cancer, and breast cancer.

 

However, in more recent times, EE is mainly used in COCs. In contraception, due to concerns of unopposed estrogen action and the possible increased risk of endometrial cancer that accompanies this, EE is formulated in combination with progestins. EE is little used in menopausal hormone replacement therapy.

 

EE has been used at very high dosages (1–2 mg/day) in the treatment of prostate cancer.

 

Contraindications

 

EE should be avoided in women with a history of or known susceptibility to thrombosis (blood clots), particularly venous thromboembolism (VTE).

 

Due to risk of cholestatic hepatotoxicity, it is widely considered that COCs containing EE should be avoided in women with a history of cholestasis of pregnancy, hepatic tumors, active hepatitis, and familial defects in biliary excretion.

 

Side effects

 

Side effects of EE are the same as for other estrogens and include breast tenderness, headache, fluid retention (bloating), nausea, dizziness, and weight gain.The estrogen component of oral contraceptives, which is almost always EE, can cause breast tenderness and fullness

 

Relative oral potency (by weight) of EE and various other estrogens

 

Estrogen Hot flashes FSH HDL cholesterol SHBG CBG Angiotensinogen
Estradiol 100 100 100 100 100 100
Estriol 30 30 20 ? ? ?
Estrone sulfate ? 90 50 90 70 150
CEEs 120 110 150 300 150 500
Equilin sulfate ? ? 600 750 600 750
Ethinyl estradiol 12,000 12,000 40,000 50,000 60,000 35,000
Diethylstilbestrol ? 340 ? 2,560 2,450 1,950
Hot flashes = clinical relief of hot flashes; FSH = suppression of FSH levels; HDL cholesterol, SHBG, CBG,
and angiotensinogen = increase in the serum levels of these hepatic proteins.

 

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Tel: +8618908447275

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