Home ProductsRaw Steroid Powders

Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9

Certification
China Hengyang Desen Biotechnology Co., Ltd. certification
China Hengyang Desen Biotechnology Co., Ltd. certification
Customer Reviews
Awesome, thanks Irina. You've actually been the fastest and most responsive so far, you're going to be getting a lottt of business from me in future.

—— Andressa Hernandez from Brazil

EllenCaisin! I test the product, it is so good! Very happy. and I gave the treats to my family, you might be the best I ever used. best service!!!

—— Gabriel Collin from Canada

Aaron Fantastic! I have received the package. Thank you very much for great packaging. If it is good quality, you must have me as a long time customer

—— Mitch Kelly from USA

Yep Koala! got package thankyou so much, Koala. I like to place another order now. how much is T3 and tren a

—— Joaquin Vega from Spain

I'm Online Chat Now

Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9

Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9
Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9 Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9 Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9

Large Image :  Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9

Product Details:
Place of Origin: China
Brand Name: ChineseHormone
Certification: GMP, ISO 9001, USP
Model Number: CAS 51-48-9
Payment & Shipping Terms:
Minimum Order Quantity: Free samples Available
Price: negotiated
Packaging Details: as your required
Delivery Time: 3-7 working days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 500-1000 kg / month
Detailed Product Description
MW: 776.87 MF: C15H11I4NO4
Appearance: White Or Light Yellow Powder Boiling Point: 231 To 233 °C
Solubility In Water: Slightly Soluble (0.105 Mg·mL−1 At 25 °C)
High Light:

raw hormone powders

,

build muscle steroids


Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9

 

Levothyroxine, also known as L-thyroxine, is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer.

 

Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels) but was withdrawn due to cardiac side effects.

 

Medical use

 

Hypothyroidism

 

Levothyroxine is typically used to treat hypothyroidism, and is the treatment of choice for people with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in people with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.

 

A subset of people with hypothyroidism treated with an appropriate dose of levothyroxine will describe continuing symptoms despite TSH levels in the normal range. In these people, further laboratory and clinical evaluation is warranted as they may have another cause for their symptoms. Furthermore, it is important to review their medications and possible dietary supplements as several medications can affect thyroid hormone levels.

 

Subclinical hypothyroidism

 

Levothyroxine is also used to treat subclinical hypothyroidism which is defined by an elevated TSH level and a normal-range free T4 level without symptoms. Such people may be asymptomatic and whether they should be treated is controversial. One benefit of treating this population with levothyroxine therapy is preventing development of hypothyroidism.

 

As such, it is recommended that treatment should be taken into account for patients with initial TSH levels > 10 mIU/L, people with elevated thyroid peroxidase antibody titers, people with symptoms of hypothyroidism and TSH levels between 5–10 mIU/L, and women who are pregnant or want to become pregnant. Oral dosing for patients with subclinical hypothyroidism is 1 µg/kg/day.

 

Myxedema coma

 

It is also used to treat myxedema coma, which is a severe form of hypothyroidism characterized by mental status changes and hypothermia. As it is a medical emergency with a high mortality rate, it should be treated in the intensive care unit with thyroid hormone replacement and aggressive management of individual organ system complications.

 
Dosage
 

Dosages vary according to the age groups and the individual condition of the person, body weight and compliance to the medication and diet. Other predictors of the required dosage are sex, BMI, deiodinase activity (SPINA-GD) and etiology of hypothyroidism. Annual or semiannual clinical evaluations and TSH monitoring are appropriate after dosing has been established.

 

Levothyroxine is taken on an empty stomach approximately half an hour to an hour before meals. As such, thyroid replacement therapy is usually taken 30 minutes prior to eating in the morning. For patients with trouble taking levothyroxine in the morning, bedtime dosing is effective as well. A recent study published in JAMA showed greater efficacy of levothyroxine when taken at bedtime.

 

Properties
Chemical formula
C15H11I4NO4
Molar mass 776.87 g·mol−1
Melting point 231 to 233 °C (448 to 451 °F; 504 to 506 K)
Solubility in water
Slightly soluble (0.105 mg·mL−1 at 25 °C)
Other mame 3,5, 3', 5'-Tetraiodo-L-thyronine
Pharmacology
ATC code
H03AA01 (WHO)
Legal status
  • ℞ (Prescription only)
Pregnancy
category
  • US: A (No risk in human studies)
Routes of
administration
Oral, intravenous
Pharmacokinetics  
Bioavailability
~100%
Metabolism
Mainly in liver, kidneys, brain and muscles
Biological half-life

 

ca. 7 days (in hyperthyroidism 3–4 days, in hypothyroidism 9–10 days)

 

Excretion
Through feces and urine
Hazards
S-phrases S22-S24/25
Related compounds
Related compounds
  • Triiodothyronine (tri-iodated)
  • Thyronine (without iodine)

 

 

 Levothyroxine (T4) L-thyroxine Synthetic Thyroid Hormone CAS 51-48-9 0

Contact Details
Hengyang Desen Biotechnology Co., Ltd.

Contact Person: Sales Manager

Send your inquiry directly to us (0 / 3000)