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|Purity (HPLC):||99% Min||Appearance :||White Powder|
|Single Impurity(HPLC) :||1.0%max||Specificton:||2mg/vial|
peptides for muscle growth,
growth hormone peptides
Nonapeptide-1 was first isolated from the yeast Streptomyces clavifer, but is now produced synthetically through recombinant genetic technology. It was first developed for its antimicrobial activities, but has since been found to be a strong inhibitor of melanin formation laboratory studies of yeast and melanoma (skin cancer) cells . Nonapeptide-1 consists of the amino acids arginine-lysine-methionine-phenylalanine-proline-tryptophan-valine.
Nonapeptide-1, also called Melanostatine™ 5, is a propriety peptide that was originally developed for its antimicrobial activities. Animal research has revealed, however, that nonapeptide-1 can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions. Animal models suggest that nonapeptide-1 can reduce synthesis of melanin and help decrease skin pigmentation to a substantial degree.
Nonapeptide-1 is of primary research interest for its ability to reduce hyperpigmentation by inhibiting the action of tyrosinase in melanin-producing cells. The ability to regulate melanin production has potential application in a number of conditions, including photodamage of the skin.
Research also suggests that nonapeptide-1 may play a role in the central nervous system where it may act on both dopaminergic receptors and opioid receptors to modify pain signaling as well as behavior. Studies in mice support the idea that nonapeptide-1 may have central actions that affect behavior and pain.
Nonapeptide-1 Usage on Skin Lightening
In cosmeceutical terms, nonapeptide-1 is a radiance promoter and whitening agentv. In technical terms it is a melanin synthesis inhibitor that works by interfering with the action of tyrosinase. Tyrosinase is the primary enzyme responsible for the synthesis of melanin in specialized cells called melanocytes. Any interference with tyrosinase prevent melanocytes from producing pigmentv. By inhibiting tyrosinase, nonapeptide-1 can help to reduce pigment production in the skin in animal studies and thus lighten darker areas that have been damaged by the sun and certain diseases.
There is some evidence that nonapeptide-1 acts by interfering with melanocyte stimulating hormone (MSH). MSH increases during pregnancy, as a result of certain medical conditions (e.g. diabetes, Addison’s disease), and as a result of excessive sun exposure. MSH is a derivative of adrenocorticotropic hormone. Synthetic analogues of MSH, such as melanotan II, mimic the effects of the natural molecule and can lead to skin darkening. Interestingly, not everyone responds to MSH. Red-heads, for instance, do not tan well because they have variations in their MSH receptors that result in poor response to MSH in the blood.
Research in fungi indicates that nonapeptide-1, at a concentration of 200 ug/mL, is capable of fully inhibiting the synthesis of melanin2. Fungi are used in this particular research because they more closely approximate conditions in human cells, but require fewer resources than animal models. Research in animal models indicates that nonapeptide-1 may effectively reduce pigmentation, after just one application, for up to 28 days at a timev. At 100 micromolar concentration, nonapeptide-1 can inhibit 25-35% of tyrosinase activity in animal models and can reduce the melanin content of melanocytes by 27-43% .
1)Location & Working Hours
We are an International source locate in China.
I will answer emails from Monday to Saturday, 8:30 am to 18:00 pm (GMT+8)
2)How long does it takes to get back a response from you?
You should receive a response in less than 24 hours.
3)How do I make an order?
When you choosed the products, please email me, and I will quote for you, if you are satisfied with it, then pay for it, the parcle will be sent for you as soon as possible.
4)How to track my order?
After I ship your order and have the tracking number, you will receive an email notification. All tracking numbers I provide can be tracked at http://www.17track.net/en. Or you can ask me for helping you track it too.
5)How long does the whole process take, from making an order till receiving the package?
The package will be prepared within 1 working day after payment received and be sent out within 72 hours.
The delivery time depends on the shipping situation and customs. The shipping time will not more than 15 working days at most.
6)How about the shipping cost?
The shipping cost is for the whole order. No matter how many different items and quantity in one orders. The shipping cost will be charged only once.
7)Is there a minimum order?
For raw powder: MOQ is 10g
For oil liquid: MOQ is 50ml
For peptide vial: MOQ is 10 vials
To U.S. We reship for free twice if your package gets seized.
To other countries we reship for free once if your package gets seized.
If you choose not to reship or the resent package failed to go through again, no refund will be made.
We accept Bank Transfer(T/T ), Western Union, Moneygram, Bitcoin.
*** The Bitboin is a little special for us, our Bitcoin account is always changing, once I gave you the account number, please pay for it at once.
Our company has a 2 reship policy all foreign countries in case of a seizure. If you fail to receive your reship(s), no refunds will be made.
**We are not responsible if you throw away your products because you cannot find them in our disguised package. If you cannot find your products please email me and I will tell you where to find them.
Product list :
|CJC-1295 with DAC||CAS: 863288-34-0|
|CJC-1295 without DAC||CAS: 863288-34-0|
|Pentadecapeptide BPC||CAS: 137525-51-0|
|HGH Fragment 176-191||CAS: 158861-67-7|
|Desmopressin Acetate||CAS: 16679-58-6|