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Raw Materials Tibolone Livial Tibofem Anti-aging Drugs CAS 630-53-5
|Synonyms||LIVIELLA; LIVIAL; 5(10)-ESTREN-7-ALPHA-METHYL-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE|
|CAS Registry Number||5630-53-5|
|Boiling point||447.4º C at 760 mmHg|
|Flash point||190.6º C|
|Vapour Pressure||6.96E-10mmHg at 25º C|
1). Tibolone is a synthetic steroid hormone drug that is nonselective in its binding profile and is primarily used as an agonist for estrogen receptors, with preference for ERα. It is mainly used for the treatment of endometriosis, as well as postmenopausal women hormone replacement therapy. Tibolone has similar or higher efficacy compared to older hormone replacement drugs, but has similar side effects. It was also investigated as a possible treatment for female sexual dysfunction.
2). Livial / Liviella is mainly used for the treatment of endometriosis, as well as postmenopausal women hormone replacement therapy. Tibolone is a synthetic steroid hormone drug that is nonselective in its binding profile and is primarily used as an agonist for estrogen receptors, with preference for ERα. Compared with the elderly hormone replacement, tibolone has similar or higher efficacy, but with similar side effects. It was also investigated for possible treatment of female sexual dysfunction.
3). When estrogen levels are low, the tissue can slowly degrade, as experienced during menopause. In addition, low levels of estrogen can cause painful symptoms such as hot flashes, night sweats, mood swings, loss of libido and vaginal dryness. Tibolone is broken down into three compounds that act in a manner similar to natural estrogen and progesterone. It regains plasma endorphin levels in postmenopausal women and focuses action to influence the thermal management system.
Tibolones is used to mimic the activity of the naturally occurring female sex hormones oestrogen and progestogen in the body,It helps to restore the natural balance of these hormones.It is used to relieve symptoms that start to occur when the female body no longer produces certain hormones such as oestrogen. In general this drug is used to treat symptoms associated with a lack of oestrogen in women who have gone through the menopause.Tibolones also helps restore hormonal balance in the body,it is broken down into three compounds which act in a similar way in the body.
Benefits of being on this drug can include replacement of lost hormones leading to an improvement in a number of symptoms including hot flushes, night sweats, dryness or irritation of the vagina and reduced sex drive. Tibolones can also reduce the likelihood of your bones becomes brittle and breaking by preventing the bone disease osteoporosis.It restores plasma endorphin level in post-menopausal women and acts centrally to affect the thermo-regulatory system.
Recommend Dosage Of Tibolione
The recommend dosage of tibolone is 2.5mg/day,optimal results are obtained when therapy is continued for at least 3 months.
Tibolone is a synthetic steroid hormone derived from the Mexican yam
The metabolites of tibolone have estrogenic, androgenic and progestogenic effects
Tibolone has oestrogen-like effects in the brain (preventing flushes), bone (preventing bone loss) and vaginal tissue (preventing dryness and soreness)
Tibolone also has progesterone-like effects at the uterus to prevent endometrial thickening and subsequent bleeding. A woman who has not had a hysterectomy does not need to take a progestogen if she is taking tibolone.
Tibolone has testosterone-like activity that appears to play a role in enhancing women's mood and libido, although response is variable.
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