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Tamoxifen / Nolvadex Anti Estrogen Steroids Fertility Inducer CAS 54965-24-1

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Tamoxifen / Nolvadex Anti Estrogen Steroids Fertility Inducer CAS 54965-24-1

Tamoxifen / Nolvadex Anti Estrogen Steroids Fertility Inducer CAS 54965-24-1
Tamoxifen / Nolvadex Anti Estrogen Steroids Fertility Inducer CAS 54965-24-1 Tamoxifen / Nolvadex Anti Estrogen Steroids Fertility Inducer CAS 54965-24-1 Tamoxifen / Nolvadex Anti Estrogen Steroids Fertility Inducer CAS 54965-24-1

Large Image :  Tamoxifen / Nolvadex Anti Estrogen Steroids Fertility Inducer CAS 54965-24-1

Product Details:
Place of Origin: China
Brand Name: ChineseHormone
Certification: GMP, ISO 9001, USP
Model Number: CAS 54965-24-1
Payment & Shipping Terms:
Minimum Order Quantity: Free samples Available
Price: negotiated
Packaging Details: as your required
Delivery Time: 3-7 working days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 500 kg / month
Detailed Product Description
MW: 563.64 Skype: Amyyc9365
MF: C26H29NO.C6H8O7 Storage: Shading, Confined Preservation
Usage: Anti-estrogen Fertility Inducer Appearance: White Crystalline Powder
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Tamoxifen / Nolvadex Anti-Estrogen Fertility Inducer CAS 54965-24-1

 

CAS : 54965-24-1
EINECS: 259-415-2
Assay: 99%
MF: C26H29NO.C6H8O7
MW: 563.64
MP: 140-144 ºC

Chemical structure:

 

  Tamoxifen / Nolvadex Anti Estrogen Steroids Fertility Inducer CAS 54965-24-1 0
Appearance: white crystalline powder
Storage: Shading, confined preservation
Drug Class: Anabolic Androgenic Steroid

Usage: the goods to anti-estrogen fertility inducer, the objects indysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases;It is used as a first line defense against breast cancer.

 

Description:

 

Tamoxifen (TMX), sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men.It is also being studied for other types of cancer. It has been used for Albright syndrome. Tamoxifen is typically taken daily by mouth for five years for breast cancer.

 

Serious side effects include a small increased risk of uterine cancer, stroke, vision problems, and pulmonary embolism. Common side effects include irregular periods, weight loss, and hot flashes. It may cause harm to the baby if taken during pregnancy or breastfeeding. It is a selective estrogen-receptor modulator (SERM) that works both by decreasing factors that increase the growth of breast cells and increasing factors that decrease the growth of breast cells.It is of the triphenylethylene group.

 

Tamoxifen was discovered in 1967. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Tamoxifen is available as a generic medication.

 

Medical uses

 

Breast cancer

 

Tamoxifen is currently used for the treatment of both early and advanced estrogen receptor (ER)-positive (ER+) breast cancer in pre- and post-menopausal women. Additionally, it is the most common hormone treatment for male breast cancer. It is also approved by the FDA for the prevention of breast cancer in women at high risk of developing the disease.[12] It has been further approved for the reduction of contralateral (in the opposite breast) cancer. The use of tamoxifen is recommended for 10 years.

 

In 2006, the large STAR clinical study concluded that raloxifene is equally effective in reducing the incidence of breast cancer, but after an average 4-year follow-up there were 36% fewer uterine cancers and 29% fewer blood clots in women taking raloxifene than in women taking tamoxifen, although the difference was not statistically significant.

 

Infertility

 

Tamoxifen is used to treat infertility in women with anovulatory disorders. It is given at days 3–7 of a woman's cycle.

Tamoxifen improves fertility in males with infertility by disinhibiting the hypothalamic-pituitary-adrenal axis (via ER antagonism) and thereby increasing the secretion of luteinizing hormone and follicle-stimulating hormone and increasing testicular testosterone production.

 

Gynecomastia

 

Tamoxifen is used to prevent estrogen-related gynecomastia, resulting from elevated estrogenic levels. It is taken as a preventative measure in small doses, or used at the onset of any symptoms such as nipple soreness or sensitivity. Other drugs are taken for similar purposes such as clomiphene citrate and the anti-aromatase drugs which are used in order to try to avoid the hormone-related adverse effects. Tamoxifen is also sometimes used to treat or prevent gynecomastia in sex offenders undergoing temporary chemical castration.

 

Others

 

Occasionally tamoxifen is used in treatment of the rare conditions of retroperitoneal fibrosis and idiopathic sclerosing mesenteritis.

 

COA:

 

Product name Tamoxifen citrate (Nolvadex)
Appearance White crystalline powder
Identification IR , UV conform Conform
Loss on drying ≤0.5ml 0.29ml
Residue on ignition Not more than 0.2% 0.07ml
Iron Not more than 0.005% 0.0027%
Heavy metals Not more than 0.001% 0.0006%
Related substances Total: Not more than 1.0%
Individual: Not more than 0.5%
0.36%
0.19%
E-isomer Not more than 0.3% 0.12%
Organic volatile impurities Conforms Conforms
Assay 97.5.0~102.0% 99.2%

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