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Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment

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Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment

China Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment supplier
Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment supplier Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment supplier Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment supplier Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment supplier

Large Image :  Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment

Product Details:

Place of Origin: China
Brand Name: Info@desen-nutrition.com
Certification: ISO9001,SGS,UKAS,GMP
Model Number: CAS 89778-27-8

Payment & Shipping Terms:

Minimum Order Quantity: Free samples Available
Price: Negotiable
Packaging Details: Discreet package or as required
Delivery Time: 3-6 working days
Payment Terms: Western Union, MoneyGram, T/T,Bitcoins
Supply Ability: 500 kg / month
Contact Now
Detailed Product Description
Email: Info@desen-nutrition.com Skype: Live:1ec72e43625dbc09
Whatsapp: 86-189 0844 6935 Packing: Discreet Packing For Customs Pass Guaranteed
Assay: 99% CAS: 89778-27-8
MF: C26H28ClNO・C6H8O7 MW: 598.09
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Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. Toremifene citrate is also being evaluated for prevention of prostate cancer under the brand name Acapodene.

 

Oral Toremifene Citrate selective estrogen receptor modulator For breast cancer treatment

 

Toremifene Citrate Quick Details:

 

Product Name Toremifene citrate
Molecular Formula C26H28ClNO・C6H8O7
Molecular Weight 598.09
CAS 89778-27-8
Molecular Structure Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment
Appearance White Crystalline Powder

 

Toremifene Citrate Descriptions:

 

In 2007 the pharmaceutical company GTx, Inc was conducting two different phase 3 clinical trials; First, a pivotal Phase clinical trial for the treatment of serious side effects of androgen deprivation therapy (ADT) (especially vertebral/spine fractures and hot flashes, lipid profile, and gynecomastia) for advanced prostate cancer, and second, a pivotal Phase III clinical trial for the prevention of prostate cancer in high risk men with high grade prostatic intraepithelial neoplasia, or PIN. Results of these trials are expected by first quarter of 2008.

 

An NDA for the first application (relief of prostate cancer ADT side effects) was submitted in Feb 2009, and in Oct 2009 the FDA said they would need more clinical data, e.g. another phase III trial.

 

Toremifene Citrate COA:

 

TEST ITEMS SPECIFICATION RESULTS
Description White or Almost White Crystalline Powder White Powder
Identification Positive Positive
Assay 97.00~103.00% 99.38%
Loss On Drying 0.5%max 0.25%
Melting Point 95~99¡ãC 96.0~98.0¡ãC
Specific Rotation +48¡ã~+51¡ã +49.0¡ã
Organic Volatile Impurities meets the requirments. Conforms
Residual Solvents meets the requirments. Conforms
Conclusion The specification conform with USP32 standard

 

Toremifene Citrate Applications:

 

It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there.

 

Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.

 

Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment

 

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Can be used as pharmaceutical material

 

Shipping:


1. Preferentially DHL or HKEMS for quantity less than 50KG;
2. Sea shipping for quantity over 60KG. 100% safe!
3. Send from our agent in Singapore, Laos, Netherlands.

 

We provide re-ship policy, So there are not any loss once you order from us and I guarantee delivery and your interests!

Contact Details
Hengyang Desen Biotechnology Co., Ltd.

Contact Person: Irina

Tel: +8618908446935

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