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|Assay:||99%||Appearance:||White Or Almost White Crystalline Powder, Odorless. Almost Insoluble In Water, Soluble In Alcohol, Chloroform, Slightly Soluble In Acetone|
|EINECS:||241-270-1||Packing:||1Kg/foil Bag Or As Required|
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Androgen Steroid Hormone Danazol CAS 17230-88-5 Selective Progesterone Receptor Modulator
|Usage:||Danazol is an anterior pituitary supressant. Danazol is an anabolic steroid derivative of ethisterone, with mild androgenic side effects (an impeded androgen).|
Danazol, sold under the brand names Danatrol, Danocrine, Danol, and Danoval among many others, is a synthetic steroid that is used primarily in the treatment of endometriosis. It was approved by the U.S. Food and Drug Administration in 1971 as the first drug in the country to specifically treat this condition.
Although it is effective for endometriosis, the use of danazol is limited by virilizing side effects such as voice deepening and hirsutism (excessive facial/body hair growth). In relation to this, the drug has largely been replaced by gonadotropin-releasing hormone (GnRH) agonists in the treatment of the condition since their introduction.
Danazol is used primarily in the treatment of endometriosis. It has also been used – mostly off-label – for other indications, namely in the management of menorrhagia, fibrocystic breast disease, immune thrombocytopenic purpura, premenstrual syndrome, breast pain, and hereditary angioedema. Although not currently a standard treatment for menorrhagia, danazol demonstrated significant relief in young women with menorrhagia in a study, and, because of a lack of a significant adverse effects, it was proposed as an alternative treatment. Low-dose danazol has also been investigated in the treatment of diabetic macular edema in a phase III clinical trial. A dosage of 800 mg/day danazol was found to increase telomere length in patients with telomere diseases in a phase I/II clinical trial.
Treating certain types of endometriosis or fibrocystic breast disease. It is also used to prevent attacks of hereditary angioedema (HAE). It may also be used for other conditions as determined by your doctor.
Danazol is a synthetic steroid. It works by decreasing the level of certain hormones, which reduces the symptoms and severity of the diseases treated by danazol.
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