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sex hormones drugs,
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Estradiol benzoate (EB, E2B) (INN) (brand name Progynon-B, many others), or oestradiol benzoate (BAN), is a semisynthetic, steroidal estrogen and an estrogen ester – specifically, the 3-benzoate ester of estradiol – which is marketed in Europe and elsewhere throughout the world. Estradiol benzoate acts as a prodrug of estradiol, and hence, is considered to be natural, bioidentical estrogen.
CAS 50-50-0 Legal Oral Steroids Estradiol Benzoate Anti Estrogen Supplements Powders
|Product name||Estradiol Benzoate|
|Other name||beta-Estradiol-3-benzoate; Oestradiol Benzoate; 17beta-Estradiol benzoate; 1,3,5(10)-Estratriene-3,17b-diol 3-benzoate; 3,17b-Dihydroxy-1,3,5(10)-estratriene 3-benzoate; (17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate; 1,3,5(10)-Estratriene-3,17-diol-3-benzoate; 1,3,5(10)-Oestratriene-3,17-beta-diol 3-benzoate; 1,3,5(10)-oestratriene-3,17-beta-diol3-benzoate; 17beta-Estradiol monobenzoate; 17-beta-estradiolmonobenzoate; 17-beta-Oestradiol 3-benzoate; 17-beta-oestradiol3-benzoate; 17-Hydroxyestra-1(10),2,4-trien-3-yl benzoate; 17β-estradiol3-benzoate; 3-(benzoyloxy)estra-1,3,5(10)-trien-17β-ol; Benovocylin; Benzestrofol; Benzhormovarine; Benzoate d'oestradiol; benzoated’oestradiol ; 17-hydroxyestra-1,3,5(10)-trien-3-yl benzoate; (17beta)-3-hydroxyestra-1,3,5(10)-trien-17-yl benzoate; (17beta)-17-hydroxyestra-1,3,5(10)-trien-3-yl benzoate|
|Appearance||white crystalline powder|
Estradiol Benzoate Descriptions:
Estradiol benzoate was introduced in 1936 and was one of the first forms of estrogen to be marketed. Along with estradiol dipropionate, it was one of the most widely used estradiol esters prior to the 1950s. However, Estradiol benzoate is now little used, having largely been superseded by longer-acting esters of estradiol like estradiol valerate and estradiol cypionate that require less frequent administration.
A single dose of 2.5 mg estradiol benzoate by intramuscular injection was found to produce plasma estradiol levels of >400 pg/mL, measured 24 hours post-injection, in a group of patients with minimal baseline levels of estradiol (due to GnRH analogue therapy with triptorelin).
Estradiol Benzoate Applications:
The medical uses of estradiol benzoate are the same as those of estradiol and other estrogens. An example of an indication for the drug is hormone replacement therapy for menopausal symptoms or hypoestrogenism.
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