|Place of Origin:||China|
|Model Number:||CAS 89778-27-8|
|Minimum Order Quantity:||Free samples Available|
|Packaging Details:||Discreet package or as required|
|Delivery Time:||2-5 working days|
|Payment Terms:||Western Union, MoneyGram, T/T,Bitcoins|
|Supply Ability:||5000 kg / month|
|Email:||Tonyraws810@gmail.com||Packing:||Discreet Packing For Customs Pass Guaranteed|
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CAS: 89778-2 Toremifene Citrate Powder selective estrogen receptor modulator For breast cancer treatment Assay 99%
Toremifene Citrate Quick Details:
Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. Toremifene citrate is also being evaluated for prevention of prostate cancer under the brand name Acapodene.
|Product Name||Toremifene citrate|
|Appearance||White Crystalline Powder|
Toremifene Citrate Descriptions:
In 2007 the pharmaceutical company GTx, Inc was conducting two different phase 3 clinical trials; First, a pivotal Phase clinical trial for the treatment of serious side effects of androgen deprivation therapy (ADT) (especially vertebral/spine fractures and hot flashes, lipid profile, and gynecomastia) for advanced prostate cancer, and second, a pivotal Phase III clinical trial for the prevention of prostate cancer in high risk men with high grade prostatic intraepithelial neoplasia, or PIN. Results of these trials are expected by first quarter of 2008.
An NDA for the first application (relief of prostate cancer ADT side effects) was submitted in Feb 2009, and in Oct 2009 the FDA said they would need more clinical data, e.g. another phase III trial.
Toremifene Citrate COA:
|Description||White or Almost White Crystalline Powder||White Powder|
|Loss On Drying||0.5%max||0.25%|
|Organic Volatile Impurities||meets the requirments.||Conforms|
|Residual Solvents||meets the requirments.||Conforms|
|Conclusion||The specification conform with USP32 standard|
Toremifene Citrate Applications:
It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there.
Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.
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Can be used as pharmaceutical material
1. Preferentially DHL or HKEMS for quantity less than 50KG;
2. Sea shipping for quantity over 60KG. 100% safe!
3. Send from our agent in Singapore, Laos, Netherlands.
We provide re-ship policy, So there are not any loss once you order from us and I guarantee delivery and your interests!
Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Xiaogan, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service
Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal.
Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.
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