Pharmaceutical Intermediates CAS 4418-61-5 Tetrazole 5-Aminotetrazole

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Model Number: 4418-61-5
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Name: 5-Aminotetrazole CAS: 4418-61-5
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Pharmaceutical Intermediates CAS 4418-61-5 Tetrazole 5-Aminotetrazole

 

Product Name:

5-Aminotetrazole

Synonyms:

1H-Tetrazole, 5-amino-;2H-Tetraazol-5-amine;5-Amino-1,2,3,4-tetrazole;5-amino-1h-tetrazol;5-Amino-2H-tetrazole;aminotetrazole;etrazole, 5-amino-;H-Tetrazol-5-ylamine

CAS:

4418-61-5

MF:

CH3N5

MW:

85.07

EINECS:

224-581-7

Product Categories:

Miscellaneous;pharmacetical;Building Blocks;Heterocyclic Building Blocks;Tetrazoles;chemical additive;fine chemicals;Pyridines

Mol File:

4418-61-5.mol

 

 

Description

 

5-aminotetrazole is one of the organic heterocyclic compounds containing a five-membered two unsaturated ring structure of four nitrogen atoms and one carbon atom. The simplest member of the tetrazole family is tetrazole itself, with a weakly characteristic odor of white to pale yellow crystalline solids; soluble in water and alcohol, melted at 156C.

 

Tetrazole is explosive. It is used as a gas generating agent for airbags. Tetrazole transport is only available in certain countries / regions. Tetrazole and its derivatives for antiviral, antibacterial, antifungal and anti-tuberculosis and other biological activity. They are used as catalysts for the synthesis of phosphonates.

 

5-aminotetrazole is an organic compound having the formula HN4CNH2. It is a white solid that can be obtained in anhydrous and hydrated form. The nitrogen content of the compound is particularly high, at 80%. In part because of this reason, the compound is easily decomposed into nitrogen (N2). Gas generation systems, such as air bags and foaming agents, have been extensively studied.

 

Applications

 

There are several pharmaceutical agents which are tetrazoles. The tetrazole ring can act as a bioisostere for thecarboxylate group. Angiotensin II receptor blockers, in particular, such as losartan and candesartan, often contain tetrazoles.

 

 

A well-known tetrazole is dimethyl thiazolyl diphenyl tetrazolium salt (MTT). This tetrazole is used in the MTT assay to quantify the respiratory activity of live cells in cell culture, although it generally kills the cells in the process. Tetrazole's derivatives can also be used in DNA synthesis.

 

Pharmaceutical Intermediates CAS 4418-61-5 Tetrazole 5-Aminotetrazole 0

 

Pharmaceutical Intermediates CAS 4418-61-5 Tetrazole 5-Aminotetrazole 1

 

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