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|Purity (HPLC):||98.0%min.||Appearance:||White Powder|
|Single Impurity (HPLC) :||0.5%max||Amino Acid Composition:||±10% Of Theoretical|
muscle building peptides,
growth hormone peptides
Desmopressin (DDAVP) is a synthetic analog of vasopressin with low vasopressor activity. Apart from its increasing effect on water resorption by the kidneys, desmopressin raises plasma levels of von Willebrand factor and factor VIII.
In veterinary medicine, desmopressin is applied in the treatment of canine and feline diabetes insipidus.
Desmopressin Acetate Human Growth Peptides 98.0%16789-98-3 DDAVP Peptide
CAS: 16789-98-3Alias: DDAVP, 1-Deamino-8-D-arginine-vasopressin diacetate, 1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin diacetate
CAS No.: 16789-98-3
Molecular Formula: C46H64N14O12S2
Molecular Weight: 1189.32
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): ≥ 80.0%
Water Content (Karl Fischer): ≤ 8.0%
Acetate Content (HPIC): ≤ 12.0%
MS (ESI): Consistent
Mass Balance: 95.0~105.0%
Grade: Pharmaceutical Grade
Storage: Closed, below 2 ~ 8º C preservation
Usage: Desmopressin Acetate is used for nocturnal enuresis, coagulation zdisorders and diabetes insipidus.
Desmopressin (trade names: DDAVP, DesmoMelt, Minirin, Minirin Melt, Octim, Stimate) is a synthetic replacement for vasopressin, the hormone that reduces urine production. It may be taken nasally, intravenously, or as an oral or sublingual tablet. Physicians prescribe desmopressin most frequently for treatment of diabetes insipidus, bedwetting, or nocturia.
Doctors prescribe desmopressin frequently for treatment of nocturnal enuresis (bedwetting). It is usually prescribed in the form of oral desmopressin acetate, DDAVP. Patients taking DDAVP are 4.5 times more likely to sleep without disruption compared with placebo.
Desmopressin can be used to promote the release of von Willebrand factor (with subsequent increase in factor VIII survival secondary to vWF complexing) in patients with coagulation disorders such as von Willebrand disease, mild hemophilia A (factor VIII deficiency), and thrombocytopenia. It can be used with uremic induced platelet dysfunction. It is not effective in the treatment of hemophilia B (factor IX deficiency), severe hemophilia A, or von Willebrand 2B.
Desmopressin is used in the treatment of central diabetes insipidus (DI), to replace endogenous ADH that is missing in the central nervous system type of this disorder (decreased production of ADH from the posterior pituitary). It is also used in the diagnostic workup for diabetes insipidus, in order to distinguish central from nephrogenic DI.
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|Ppearance||White or almost white powder|
|Clarity and color of solution||Clear, colorless solution|
|Loss on drying||≤1.0%|
|Bacterial endotoxins||≤ 0.25 EU/mg|
|Related substances||Individual impurity:≤ 1.0%|
|Single impurity (HPLC)||0.5%max|
|Amino acid composition||± 10% of theoretical|
|Peptide content (n%)||≥ 80.0%|
|Water content (karl fischer)||≤ 8.0%|
|Acetate content (hpic)||≤ 12.0%|
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