Paracetamol White Raw Pain Killer Powder for Reducing Fever and Relieving Pain CAS 103-90-2

Paracetamol White Raw Powder for Reducing Fever and Relieving Pain CAS 103-90-2

Description:

Paracetamol, also known as acetaminophen or APAP, is a medication used to treat pain and fever. It is typically used for mild to moderate pain.There is poor evidence for fever relief in children. It is often sold in combination with other ingredients such as in many cold medications.

In combination with opioid pain medication, paracetamol is used for more severe pain such as cancer pain and after surgery. It is typically used either by mouth or rectally but is also available intravenously. Effects last between two and four hours.

Paracetamol is generally safe at recommended doses. Serious skin rashes may rarely occur, and too high a dose can result in liver failure. It appears to be safe during pregnancy and when breastfeeding. In those with liver disease, it may still be used, but lower doses should be taken.Paracetamol is classified as a mild analgesic.It does not have significant anti-inflammatory activity and how it works is not entirely clear.

Paracetamol was discovered in 1877. It is the most commonly used medication for pain and fever in both the United States and Europe.It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. Paracetamol is available as a generic medication with trade names including Tylenol and Panadol among others.

Medical uses

• Fever

• Pain

• Osteoarthritis

• Low back pain

• Postoperative pain

Veterinary use

Cats

Paracetamol is extremely toxic to cats, which lack the necessary glucuronyl transferase enzymes to break it down safely. Initial symptoms include vomiting, salivation, and discoloration of the tongue and gums.

Unlike an overdose in humans, liver damage is rarely the cause of death; instead, methemoglobin formation and the production of Heinz bodies in red blood cells inhibit oxygen transport by the blood, causing asphyxiation (methemoglobemia and hemolytic anemia).

Treatment with N-acetylcysteine,methylene blue or both is sometimes effective after the ingestion of small doses of paracetamol.

Dogs

Although paracetamol is believed to have no significant anti-inflammatory activity, it has been reported as effective as aspirin in the treatment of musculoskeletal pain in dogs.

A paracetamol-codeine product (trade name Pardale-V) licensed for use in dogs is available on veterinary prescription in the UK. It should be administered to dogs only on veterinary advice and with extreme caution.

The main effect of toxicity in dogs is liver damage, and GI ulceration has been reported.N-acetylcysteine treatment is efficacious in dogs when administered within 2 hours of paracetamol ingestion.

Snakes

Paracetamol is also lethal to snakes, and has been suggested as a chemical control program for the invasive brown tree snake (Boiga irregularis) in Guam.Doses of 80 mg are inserted into dead mice scattered by helicopter.

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