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Anti Estrogen Letrozole Breast Cancer Steroids For Hormonally - Responsive

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Anti Estrogen Letrozole Breast Cancer Steroids For Hormonally - Responsive

Anti Estrogen Letrozole Breast Cancer Steroids For Hormonally - Responsive
Anti Estrogen Letrozole Breast Cancer Steroids For Hormonally - Responsive Anti Estrogen Letrozole Breast Cancer Steroids For Hormonally - Responsive Anti Estrogen Letrozole Breast Cancer Steroids For Hormonally - Responsive

Large Image :  Anti Estrogen Letrozole Breast Cancer Steroids For Hormonally - Responsive

Product Details:
Place of Origin: China
Brand Name: ChineseHormone
Certification: GMP, ISO 9001, USP
Model Number: CAS 112809-51-5
Payment & Shipping Terms:
Minimum Order Quantity: Free samples Available
Price: negotiated
Packaging Details: as your required
Delivery Time: 3-7 working days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 500-1000 kg / month
Detailed Product Description
MW: 285.3027 MF: C17H11N5
Melting Point: 184-185 °C Half Life: 2 Days
Shipment: FedEx, TNT, EMS, DHL.UPS,EUB Email: Tonyraws810@gmail.com
Whatsapp: 86-15871352379 Wickr: Tonyraws
High Light:

anti estrogen supplements for men

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natural anti estrogen

 

Letrozole Anti Estrogen Steroids for Hormonally-Responsive Breast Cancer

 

CAS number:112809-51-5

WeightAverage: 285.3027
Monoisotopic: 285.101445377

Chemical Formula: C17H11N5

chemical structure:

 

Anti Estrogen Letrozole Breast Cancer Steroids For Hormonally - Responsive 0

Half life:2 days

melting point:184-185 °C

 

Letrozole (INN, trade name Femara) is an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery.

 

Uses

 

FDA-approved use

 

Femara 2.5 mg oral tablet

Letrozole is approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women.

 

Off-label uses

 

Letrozole has been used for ovarian stimulation by fertility doctors since 2001 because it has fewer side-effects than clomiphene (Clomid) and less chance of multiple gestation. A study of 150 babies following treatment with letrozole or letrozole and gonadotropins presented at the American Society of Reproductive Medicine 2005 Conference found no difference in overall abnormalities but did find a significantly higher rate of locomotor and cardiac abnormalities among the group having taken letrozole compared to natural conception.

 

A larger, follow-up study with 911 babies compared those born following treatment with letrozole to those born following treatment with clomiphene. That study also found no significant difference in the rate of overall abnormalities, but found that congenital cardiac anomalies was significantly higher in the clomiphene group compared to the letrozole group. Despite this, India banned the usage of letrozole in 2011, citing potential risks to infants. In 2012, an Indian parliamentary committee said that the drug controller office colluded with letrozole's makers to approve the drug for infertility in India and also stated that letrozole's use for infertility was illegal worldwide;however, such off-label uses are legal in many countries such as the US and UK.

 

The anti-estrogen action of letrozole has been shown to be useful in pretreatment for termination of pregnancy, in combination with misoprostol. It can be used in place of mifepristone, which is expensive and unavailable in many countries.

 

Letrozole is sometimes used as a treatment for gynecomastia, although it is probably most effective at this if caught in an early stage (such as in users of anabolic steroids).

 

Some studies have shown that letrozole can be used to promote spermatogenesis in male patients suffering from nonobstructive azoospermia.

 

Letrozole has also been shown to delay the fusing of the growth plates in mice. When used in combination with growth hormone, letrozole has been shown effective in one adolescent boy with a short stature.

Letrozole has also been used to treat endometriosis.

 

Predicted Properties

 

Water Solubility 0.0799 mg/mL ALOGPS
logP 1.86 ALOGPS
logP 2.94 ChemAxon
logS -3.5 ALOGPS
pKa (Strongest Basic) 2.17 ChemAxon
Physiological Charge 0 ChemAxon
Hydrogen Acceptor Count 4 ChemAxon
Hydrogen Donor Count 0 ChemAxon
Polar Surface Area 78.29 Å2 ChemAxon
Rotatable Bond Count 3 ChemAxon
Refractivity 94.47 m3·mol-1 ChemAxon
Polarizability 29.59 Å3 ChemAxon
Number of Rings 3 ChemAxon
Bioavailability 1 ChemAxon
Rule of Five Yes ChemAxon
Ghose Filter Yes ChemAxon
Veber's Rule Yes ChemAxon
MDDR-like Rule Yes ChemAxon

 

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Email: tonyraws810@gmail.com

Whatsapp: 86-15871352379

Wickr: tonyraws

 

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