|Place of Origin:||China|
|Certification:||GMP, ISO 9001, USP, BP|
|Minimum Order Quantity:||Free samples Available|
|Packaging Details:||As requires|
|Delivery Time:||Within 3 working days|
|Payment Terms:||T/T, Western Union, MoneyGram|
|Appearance:||White Or Milky White Crystalline Powder||MP:||263-269 °C|
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Ethisterone was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin. It was derived from testosterone via ethynylation at the C17α position, and it was hoped, that, analogously to estradiol and ethinylestradiol, ethisterone would be an orally active form of testosterone.However, the androgenic activity of ethisterone was attenuated and it showed considerable progestogenic activity.As such, it was developed as a progestogen instead and was marketed in Germany in 1939 as Proluton C and by Schering in the U.S. in 1945 as Pranone, among other brand names.
99.9% Legal progestogen hormone Ethisterone Raw Steroid Powders CAS 434-03-7
CAS No.: 434-03-7
Molecular Weight: 312.49
Appearance: Off-white powder
Package: 1kg/foil bag or according to the customers requirements.
Density: 1.13 g/cm3
Melting Point: 263-269 °C(lit.)
Boiling Point: 446.4 °C at 760mmHg
Flash Point: 190.2 °C
Storage: Keep it under seal in cool and dark place
Ethisterone (pregneninolone, 17α-ethynyltestosterone or 19-norandrostane) is a progestin. It is the 17α-ethynyl analog of testosterone, and was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U.S. in 1945 as Pranone. It was the first orally-active progestin.
Ethisterone was also marketed in the U.S. from the 1950s into the 1960s under a variety of trade names by other pharmaceutical companies that had been members of the pre-World War II European hormone cartel (Ciba, Organon, Roussel).
Ethisterone is a metabolite . Ethisterone is a progestogen hormone. The first orally active progestin.This compound belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.
Potent progestin. Progesterone and androgen receptor antagonist.
Ethisterone is a progestogen that counteracts estrogenic proliferative effects on the endometrium.
Ethisterone is a progestogen hormone being considered to treat prostate cancer
Synthetic progestogen; metabolite ; intermediate in the synthesis of Spironolacton.Similar to the yellow like progesterone, for the treatment of excessive menstrual bleeding, or sub-camps can also be used to prevent threatened abortion and habitual abortion. Progesterone is a progestin by the corpus luteum and the placenta secreted is more than the synthetic.
The first orally active progestin, ethisterone (pregneninolone, 17α -ethynyltestosterone or 19-norandrostane), the 17α -ethynyl analog of testosterone, was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U. S. In 1945 as Pranone.
Ethisterone was also marketed in the U. S. From the 1950s into the 1960s under a variety of trade names by other pharmaceutical companies that had been members of the pre-World War II European hormone cartel (Ciba, Organon, Roussel).
The treatment of dysfunctional uterine bleeding: Take 1 2.5mg every 8 hours, (in case of emergency medicine 1 times every 3 hours, until the bleeding decreased obviously changed after 8 hours 1 times), and then gradually reduced, until the maintenance dose of 2.5mg 1 times daily, and even last 20 days; Also can be in the bleeding stops, daily add oral ethinyl estradiol 0.05mg or diethylstilbestrol 1mg, total 20 days.
Infertility: Oral Ethisterone 2.5mg and ethinylestradiol 0.05mg, 1 times a day, and even last 20 days, total of 3 cycles.
Dysmenorrhea, endometriosis: Begin 5-7 days after menstruation, orally 1 times daily 2.5mg, and even last 20 days.
|Description||White or Almost White Crystalline Powder||white powder|
|Loss On Drying||1.0%max||0.27%|
|Organic Volatile Impurities||meets the requirement.||Conforms|
|Related Substances||meets the requirement.||Conforms|
|Residual Solvents||meets the requirement.||Conforms|
|Particle Size||100% ≤ 20 microns||Conforms|
|Conclusion||The specification conform with USP30 standard|
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|Name||CAS No.||Name||CAS No.|
|Ethynodiol diacetate||297-76-7||Chlormadinone acetate||302-22-7|
|Cyproterone acetate||427-51-0||Megestrol acetate||595-33-5|
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