Clostebol CAS 1093-58-9 Oral Anabolic Steroids Legal Anabolic Steroids 4-Chlorotestosterone

Clostebol (brand names Steranabol, Test-Anabol), also known as 4-chlorotestosterone, usually as the ester clostebol acetate, is a synthetic anabolic androgenic steroid. Clostebol is the 4-chloro derivative of the natural hormone testosterone. The chlorination prevents conversion to dihydrotestosterone (DHT) while also rendering the chemical incapable of conversion to estrogen.

Clostebol CAS 1093-58-9 White Powder 4-chlorotestosterone For performance enhancing drug

Clostebol Quick Detail:

Product Name	Clostebol
Alias	4-chloro-17-beta-hydroxyandrost-4-en-3-one; (17beta)-4-chloro-17-hydroxyandrost-4-en-3-one; Steranabol, Test-Anabol; 4-chlorotestosterone
MF	C19H27ClO2
MW	322.8695
CAS	1093-58-9
EINECS	214-133-9
Molecular Structure
Appearance	White crystalline powder

Clostebol Descriptions:

Clostebol is a weak anabolic steroid with potential use as a performance enhancing drug. Clostebol is currently banned by the World Anti-Doping Agency. Oral Turinabol, combining the chemical structures of clostebol and dianabol, was widely used in the East German state-sponsored doping program.

Clostebol Applications:

Clostebol is a synthetic androgenic steroid with anabolic effects that is frequently used in sports to increase physical performance.

Clostebol acetate ointment has ophthalmological and dermatological use.

Chlorotestosterone is a very simple derivative of testosterone made by attaching a chlorine atom at the 4 position. This slight modification makes for a very different molecule than testosterone. Clostebol has a slightly lower binding affinity for the AR than testosterone and no binding to the PR or GR. The chlorine atom blocks the action of aromatase on this molecule. This means that chlorotestosterone cannot be converted to estrogen and is converted to a less potent DHT derivative1. Because testosterone is converted to DHT and estrogen to some degree and because DHT and estrogen are inactive in muscle tissue, you lose a good portion of activity when using testosterone.

You also lose some of testosterone’s activity due to binding to SHBG. Chlorotestosterone binds much more weakly to SHBG than testosterone does. This makes clostebol a very good choice as an anabolic as can be seen from the anabolic to androgenic ratio. This steroid was marketed with an acetate ester requiring daily injections. It is surprising that chlorotestosterone is not used more often but this is probably due to the fact that this steroid does not offer instant gratification in the form of “bloat”. A longer ester would make this steroid much more attractive.

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