| Place of Origin: | China |
|---|---|
| Brand Name: | ChineseHormone |
| Certification: | ISO9001,SGS,UKAS |
| Model Number: | CAS 53-41-8 |
| Minimum Order Quantity: | Free samples Available |
| Price: | negotiated |
| Packaging Details: | as your required |
| Delivery Time: | 3-7 working days |
| Payment Terms: | Western Union, MoneyGram, T/T, Bitcoin |
| Supply Ability: | 500-1000kg / month |
| MF: | C19H30O2 | MW: | 290.440 |
|---|---|---|---|
| Alias: | 3α-hydroxy-5α-androstan-17-one, | Water Solubility:: | 0.0063 Mg/mL |
| Appearance: | White To Light Beige Crystalline Powder | Shipment: | FedEx, TNT, EMS, DHL.UPS,EUB |
| Email: | Tonyraws810@gmail.com | Whatsapp: | 86-15871352379 |
| Wickr: | Tonyraws | ||
| High Light: | sex hormones drugs,natural anti estrogen |
||
Androsterone Anti Estrogen Raw Steroids White Crystalline Powders CAS 53-41-8
Formula :C19H30O2
CAS Number :53-41-8
Molar mass: 290.440 g/mol
MP: 181-184 °C(lit.)
Storage temp. : −20°C
Alpha : 96 º (c=1, C2H5OH)
Water Solubility:0.0063 mg/mL
Appearance:white to light beige crystalline powder
Usage:Antihypertensor.It was isolated from male urine after removed of the phenolic estrogen fraction
Description:
Androsterone is an inactive breakdown metabolite of testosterone, the product of a reaction mediated by the enzyme oxidative 17beta-hydroxysteroid dehydrogenase (EC 1.1.1.51, 17beta-HSD). Androsterone is also can be metabolized from other adrenal androgens such as dehydroepiandrosterone, dihydrotestosterone or androstenedione, and is considered an inactive end product; however, it can be a physiological effector in its own right.
Androsterone might be converted back to dihydrotestosterone. Humans (and other primates) are unique among mammals in having high levels of circulating androsterone glucuronide, a process that is the major role uridine-diphospho-glucuronosyltransferase (EC 2.4.1.17, UGT) enzymes for glucuronidation of steroid metabolism in humans.
Conjugation of androsterone is a pathway found in all vertebrates and is widely recognized that the liver is a major site of glucuronidation; however it is now clear that extrahepatic tissues are also involved in the conjugation of compounds to which these tissues are exposed. High levels of androsterone glucuronide found in the human prostate, breast cyst fluid and ovary follicular fluid suggest that glucuronidation of 5alpha-reduced C19 steroids occurs in these tissues as well.
In doping control, the ratio of androsterone/etiocholanone provides valuable information that allows the assignment of a urine specimen to a particular person or the identification of urine samples with identical steroid profiles; this is particularly important to detect attempts of urine manipulation including urine alteration and substitution.
| Ontology | |
|---|---|
| Status | Detected and Quantified |
| Origin |
Endogenous Food |
| Biofunction |
Cell signaling Fuel and energy storage Fuel or energy source Hormones, Membrane component Membrane integrity/stability |
| Application |
Nutrients Stabilizers Surfactants and Emulsifiers |
| Cellular locations |
Cytoplasm Extracellular Membrane (predicted from logP) Endoplasmic reticulum |
| Property | Value | Source |
|---|---|---|
| Water Solubility | 0.0063 mg/mL | ALOGPS |
| logP | 3.71 | ALOGPS |
| logP | 3.77 | ChemAxon |
| logS | -4.7 | ALOGPS |
| pKa (Strongest Acidic) | 18.3 | ChemAxon |
| pKa (Strongest Basic) | -1.4 | ChemAxon |
| Physiological Charge | 0 | ChemAxon |
| Hydrogen Acceptor Count | 2 | ChemAxon |
| Hydrogen Donor Count | 1 | ChemAxon |
| Polar Surface Area | 37.3 Å2 | ChemAxon |
| Rotatable Bond Count | 0 | ChemAxon |
| Refractivity | 83.81 m3·mol-1 | ChemAxon |
| Polarizability | 34.7 Å3 | ChemAxon |
| Number of Rings | 4 | ChemAxon |
| Bioavailability | 1 | ChemAxon |
| Rule of Five | Yes | ChemAxon |
| Ghose Filter | Yes | ChemAxon |
| Veber's Rule | Yes | ChemAxon |
| MDDR-like Rule | Yes | ChemAxon |
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Email: tonyraws810@gmail.com
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