Paclitaxel / Taxol Raw Powder Effective Anti-Cancer Drug Oncology Drug

Basic Information
Place of Origin: China
Brand Name: ChineseHormone
Certification: GMP, ISO 9001, USP
Model Number: CAS No 33069-62-4
Minimum Order Quantity: Free samples Available
Price: negotiated
Packaging Details: as your required
Delivery Time: 3-7 working days
Payment Terms: Western Union, MoneyGram, T/T.Bitcoin
Supply Ability: 500 kg / month
MW: 853.906 MF: C47H51NO14
Biological Half-life: 5.8 Hours Usage: Anti Cancer Drugs
Bioavailability: 6.5% (oral) Appearance: White Powder
Protein Binding: 89 To 98% Alias: Abraxane, Taxol, Onxol, Nov-Onxol
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Paclitaxel / Taxol Raw Powder Effective Anti-Cancer Drug Oncology Drug

 

Trade names :Abraxane, Taxol, Onxol, Nov-Onxol

Bioavailability: 6.5% (oral)

Protein binding :89 to 98%

Biological half-life :5.8 hours

CAS Number :33069-62-4

Formula :C47H51NO14

Molar mass:853.906 g/mol

 

Paclitaxel is used for:

 

Treating breast cancer in certain patients. It is also used along with carboplatin to treat non-small cell lung cancer in certain patients. It is also used along with gemcitabine to treat cancer of the pancreas. It may also be used for other types of cancer as determined by your doctor.

 

Paclitaxel is a chemotherapy medicine. It works by slowing or stopping cancer cells from dividing and growing, so they eventually die.

 

How you have paclitaxel

 

You usually have paclitaxel as an injection into a vein. It can cause an allergic reaction. To try to prevent this, you have a steroid injection and tablets before the paclitaxel drip. You also have an antihistamine (such as chlorphenamine) into a vein about an hour before your treatment. You will also have a medicine to prevent heartburn, such as ranitidine or cimetidine. Abraxane does not usually cause an allergic reaction so you don't need the anti allergy drugs with abraxane.

 

You can have paclitaxel through a thin, short tube (a cannula) put into a vein in your arm each time you have treatment. Or you may have it through a central line, a portacath or a PICC line. These are long, plastic tubes that give the drugs directly into a large vein in your chest. You have the tube put in just before your course of treatment starts and it stays in place as long as you need it.

 

You usually have chemotherapy as a course of several cycles of treatment. The treatment plan for paclitaxel depends on which cancer you have. You can find out about how doctors plan chemotherapy in the chemotherapy section.

 

Paclitaxel side effects are listed below. You can use the underlined links to find out more about each side effect. Where there is no link, use the search box at the top of the page or go to our cancer drugs side effects section.

 

Paclitaxel / Taxol Raw Powder Effective Anti-Cancer Drug Oncology Drug 0

 

COA:

 

Appearance

White or almost white crystalline powder

Identification

FT-IR

HPLC

NMR

Mass

Solubility

Soluble in ethanol, methanol, Chloroform, hardly soluble in water

Specific Optical Rotation

-49.0º ~ -55.0º at 20°C

Melting Point

213°C-216°C

Water

≤1.0%

Residual Solvent

Meets the requirements of ICH

Ethyl Acetate

≤5000ppm

Acetone

≤5000ppm

Methanol

≤3000ppm

Acetic acid

≤5000ppm

Residual of volatile Solvents

Meets the requirements of ICH

Chloroform

≤60ppm

Dichloromethane

≤600ppm

Hexane

≤290ppm

Toluene

≤890ppm

Residue on Ignition

≤0.2%

Bacteria endotoxins

≤0.4 USP EU/mg

Total aerobic microbial count

≤100 cfu/g

Staphylococcus aureus

Absence

Pseudomonas aeruginosa

Absence

Salmonella species

Absence

Escherichia Coli

Absence

Heavy Metals

≤20 ppm

IMPURITIES:

10-Deacetyl Baccatin III

≤0.1%

Baccatin III

≤0.2%

Photodegradant

≤0.1%

10-Deacetyl Paclitaxel

≤0.5%

2-Debenzoylpaclitaxel-2-pentenoate

≤0.7%

Oxetane ring opened, Acetyl and benzoyl

≤0.1%

10-Acetoacetyl paclitaxel

≤0.1%

10-Deacetyl-7-epi-paclitaxel

≤0.3%

 

≤0.4%

7-epi-paclitaxel

≤0.4%

10,13-Bissidechainpaclitaxel

≤0.5%

7-Acetyl Paclitaxel

≤0.6%

 

 

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