Place of Origin: | China |
---|---|
Brand Name: | ChineseHormone |
Certification: | GMP, ISO 9001, USP |
Model Number: | CAS No 33069-62-4 |
Minimum Order Quantity: | Free samples Available |
Price: | negotiated |
Packaging Details: | as your required |
Delivery Time: | 3-7 working days |
Payment Terms: | Western Union, MoneyGram, T/T.Bitcoin |
Supply Ability: | 500 kg / month |
MW: | 853.906 | MF: | C47H51NO14 |
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Biological Half-life: | 5.8 Hours | Usage: | Anti Cancer Drugs |
Bioavailability: | 6.5% (oral) | Appearance: | White Powder |
Protein Binding: | 89 To 98% | Alias: | Abraxane, Taxol, Onxol, Nov-Onxol |
Email: | Tonyraws810@gmail.com | Whatsapp: | 86-15871352379 |
Wickr: | Tonyraws | ||
High Light: | raw pharmaceutical materials,raw materials for pharmaceutical products |
Paclitaxel / Taxol Raw Powder Effective Anti-Cancer Drug Oncology Drug
Trade names :Abraxane, Taxol, Onxol, Nov-Onxol
Bioavailability: 6.5% (oral)
Protein binding :89 to 98%
Biological half-life :5.8 hours
CAS Number :33069-62-4
Formula :C47H51NO14
Molar mass:853.906 g/mol
Paclitaxel is used for:
Treating breast cancer in certain patients. It is also used along with carboplatin to treat non-small cell lung cancer in certain patients. It is also used along with gemcitabine to treat cancer of the pancreas. It may also be used for other types of cancer as determined by your doctor.
Paclitaxel is a chemotherapy medicine. It works by slowing or stopping cancer cells from dividing and growing, so they eventually die.
How you have paclitaxel
You usually have paclitaxel as an injection into a vein. It can cause an allergic reaction. To try to prevent this, you have a steroid injection and tablets before the paclitaxel drip. You also have an antihistamine (such as chlorphenamine) into a vein about an hour before your treatment. You will also have a medicine to prevent heartburn, such as ranitidine or cimetidine. Abraxane does not usually cause an allergic reaction so you don't need the anti allergy drugs with abraxane.
You can have paclitaxel through a thin, short tube (a cannula) put into a vein in your arm each time you have treatment. Or you may have it through a central line, a portacath or a PICC line. These are long, plastic tubes that give the drugs directly into a large vein in your chest. You have the tube put in just before your course of treatment starts and it stays in place as long as you need it.
You usually have chemotherapy as a course of several cycles of treatment. The treatment plan for paclitaxel depends on which cancer you have. You can find out about how doctors plan chemotherapy in the chemotherapy section.
Paclitaxel side effects are listed below. You can use the underlined links to find out more about each side effect. Where there is no link, use the search box at the top of the page or go to our cancer drugs side effects section.
COA:
Appearance |
White or almost white crystalline powder |
Identification |
FT-IR |
HPLC |
|
NMR |
|
Mass |
|
Solubility |
Soluble in ethanol, methanol, Chloroform, hardly soluble in water |
Specific Optical Rotation |
-49.0º ~ -55.0º at 20°C |
Melting Point |
213°C-216°C |
Water |
≤1.0% |
Residual Solvent |
Meets the requirements of ICH |
Ethyl Acetate |
≤5000ppm |
Acetone |
≤5000ppm |
Methanol |
≤3000ppm |
Acetic acid |
≤5000ppm |
Residual of volatile Solvents |
Meets the requirements of ICH |
Chloroform |
≤60ppm |
Dichloromethane |
≤600ppm |
Hexane |
≤290ppm |
Toluene |
≤890ppm |
Residue on Ignition |
≤0.2% |
Bacteria endotoxins |
≤0.4 USP EU/mg |
Total aerobic microbial count |
≤100 cfu/g |
Staphylococcus aureus |
Absence |
Pseudomonas aeruginosa |
Absence |
Salmonella species |
Absence |
Escherichia Coli |
Absence |
Heavy Metals |
≤20 ppm |
IMPURITIES: |
|
10-Deacetyl Baccatin III |
≤0.1% |
Baccatin III |
≤0.2% |
Photodegradant |
≤0.1% |
10-Deacetyl Paclitaxel |
≤0.5% |
2-Debenzoylpaclitaxel-2-pentenoate |
≤0.7% |
Oxetane ring opened, Acetyl and benzoyl |
≤0.1% |
10-Acetoacetyl paclitaxel |
≤0.1% |
10-Deacetyl-7-epi-paclitaxel |
≤0.3% |
|
≤0.4% |
7-epi-paclitaxel |
≤0.4% |
10,13-Bissidechainpaclitaxel |
≤0.5% |
7-Acetyl Paclitaxel |
≤0.6% |
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Email: tonyraws810@gmail.com
Whatsapp: 86-15871352379
Wickr: tonyraws