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Rapamycin / Sirolimus Raw Powder Immunosuppressant for Lymphangioleiomyomatosis

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Rapamycin / Sirolimus Raw Powder Immunosuppressant for Lymphangioleiomyomatosis

Rapamycin / Sirolimus Raw Powder Immunosuppressant for Lymphangioleiomyomatosis
Rapamycin / Sirolimus Raw Powder Immunosuppressant for Lymphangioleiomyomatosis Rapamycin / Sirolimus Raw Powder Immunosuppressant for Lymphangioleiomyomatosis

Large Image :  Rapamycin / Sirolimus Raw Powder Immunosuppressant for Lymphangioleiomyomatosis

Product Details:
Place of Origin: China
Brand Name: ChineseHormone
Certification: ISO9001,SGS,UKAS
Model Number: CAS 53123-88-9
Payment & Shipping Terms:
Minimum Order Quantity: 1g
Price: negotiated
Packaging Details: as your required
Delivery Time: 3-7 working days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 5 KG / month
Detailed Product Description
Purity: 99.0% MW: 914.1719
Alias: Rapamycin / Sirolimus Water Solubility: 0.00173 Mg/mL
MF: C51H79NO13 Appearence: White Powder
Email: Tonyraws810@gmail.com Whatsapp: 86-15871352379
Wickr: Tonyraws
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Rapamycin / Sirolimus Raw Powder Immunosuppressant for Lymphangioleiomyomatosis

 

Sirolimus (INN/USAN), also known as rapamycin, is a macrolide compound produced by the bacterium Streptomyces hygroscopicus that is used in medicine to prevent organ transplant rejection and to treatlymphangioleiomyomatosis.

 

It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits activation of T cells and B cells by reducing the production of interleukin-2 (IL-2). Sirolimus is also used as a coating for coronary stents.

 

Sirolimus was isolated for the first time in 1972 by Suren Sehgal and colleagues from samples of Streptomyces hygroscopicus found on Easter Island. The compound was originally named rapamycin after the native name of the island, Rapa Nui.Sirolimus was initially developed as an antifungal agent.

 

However, this use was abandoned when it was discovered to have potent immunosuppressive and antiproliferative properties due to its ability to inhibit mTOR. It was approved by the US Food and Drug Administration in September 1999 and is marketed under the trade name Rapamune by Pfizer (formerly byWyeth).

 

How to use sirolimus

 

Use sirolimus as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

       1

Sirolimus comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get sirolimus refilled.

 

       2

Sirolimus comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get sirolimus refilled.

 

       3

You may take sirolimus by mouth on an empty stomach or with food. However, you must take it the same way each time for it to work best. If you take sirolimus on an empty stomach, always take it on an empty stomach. If you take it with food, always take it with food.

 

       4

Swallow sirolimus whole. Do not break, crush, or chew before swallowing. If you cannot swallow sirolimus whole, check with your doctor.

 

       5

Wash your hands immediately after taking sirolimus.

 

       6

If you are also taking cyclosporine, take sirolimus 4 hours after your cyclosporine dose unless your doctor tells you otherwise.

 

       7

Grapefruit and grapefruit juice may increase the risk of side effects from sirolimus. Do not eat grapefruit or drink grapefruit juice while taking sirolimus.

 

       8

Sirolimus works best if it is taken at the same time each day. Continue to take sirolimus even if you feel well. Do not miss any doses.

 

       9

Do not stop taking sirolimus without first checking with your doctor.

 

     10

If you miss a dose of sirolimus, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

 

 

Rapamycin / Sirolimus Raw Powder Immunosuppressant for Lymphangioleiomyomatosis 0

 

Adverse effects

System Adverse effects
Body as a Whole Sepsis, lymphocele, herpes zoster infection, herpes simplex infection
Cardiovascular Venous thromboembolism (pulmonary embolism and deep venous thrombosis), rapid heart rate
Digestive Stomatitis
Hematologic/Lymphatic Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS), leukopenia
Metabolic Abnormal healing, increased lactic dehydrogenase (LDH), hypokalemia, diabetes
Musculoskeletal Bone necrosis
Respiratory Pneumonia, epistaxis
Skin Melanoma, squamous cell carcinoma, basal cell carcinoma
Urogenital Pyelonephritis, ovarian cysts, menstrual disorders (amenorrhea and menorrhagia)

 

 

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