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Assay: | 99% | Character: | White Powder |
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EINECS: | 208-768-0 | Packing: | 1Kg/foil Bag Or As Required |
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CAS 541-15-1 99% Purity Fat Loss Hormones Supplement ISO9001 Listed
Alias:3-Hydroxy-4-(trimethylammonio)butanoate;Vitamin BT
CAS:541-15-1
EINECS:208-768-0
FEMA:3484
MF:C7H15NO3
MW:161.2
MP:208-212ºC
Water solubility:2500G/L(20ºC)
Assay:99%
Appearance: White powder
Specification: CP
Product Name: | L-carnitine |
Synonyms: | 3- CARBOXY-N,N,N-TRIMETHYL-2-PROPEN-1-AMINIUM CHLORIDE;3-HYDROXY-4-(TRIMETHYLAMMONIO)-BUTANOAT;3-HYDROXY-GAMMA-(TRIMETHYLAMMONIO)-BUTYRATE;LEVOCARNITINE;L-CARNITHINE;L-CARNITIN;L(-)-CARNITINE;L-CARNITINE |
CAS: | 541-15-1 |
MF: | C7H15NO3 |
MW: | 161.2 |
EINECS: | 208-768-0 |
Melting point: | 197-212 °C(lit.) |
alpha: | -31 º (c=10, H2O) |
storage temp: | 2-8°C |
Water Solubility: | 2500 g/L (20 ºC) |
Mol File: | 541-15-1.mol |
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Description:
L-carnitine has a similar chemical structure with choline. Although with similar structure as amino acids, but it is not an amino acid because it is not involved in the biosynthesis of proteins. Since L-carnitine can be de novo synthesized by human and most kinds of animals to meet the physical demands, so it is not a vitamin in the true sense, but just a vitamin-like substance.
L-carnitine is easily soluble in water with dietary carnitine being able to be completely absorbed by the body. The known in vivo absorption position of L-carnitine is the small intestine, but the exact absorption mechanism by which carnitine (free or esterified) penetrating through the intestine mucosa as well as exact site of intestinal absorption are unclear. Beside the intake of exogenous L-carnitine from food, humans can also de novo synthesize
endogenous carnitine themselves.
Liver and kidneys are the main organs of synthesizing carnitine biosynthesis, starting from lysine via ε- trimethyl -β-hydroxy-lysine, and generate γ-butyl betaine through aldolase and aldehyde oxidase, finally be converted to L-carnitine through hydroxylase. In addition to lysine, the L-carnitine biosynthesis in vivo also requires methionine and vitamin C, niacin and vitamin B6.
Anatomy of rats has found that the highest concentration of carnitine is found in the adrenal glands, heart, bone, muscle, followed by adipose tissue and the liver, wherein the concentration in kidney and brain is 40 times as high as that in the blood.
Owing to the different measurement method as well as the difference in experimental subject, the concentrations of carnitine in the body also varies with great fluctuation. Biological measurement has found that human plasma carnitine content is between 0.86 ~ 2.87mg/100mL. Method of Enzymology has found that muscle carnitine content is between 0.457 ~ 2.479μg/g (dry basis). Absorbed carnitine by the human body metabolism is excreted through urine in the form of the free carnitine.
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