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|Assay:||98.5%||Character:||White Or Nearly White Crystalline Powder|
|MF:||C19H30O2||Packing:||1Kg/foil Bag Or As Required|
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Androstenediol 521-17-5 anabolic androgen steroid hormone muscle bodybuilding
Appearance:White crystalline powder
The value of Δ5-diol as a radiation countermeasure is based mainly on its stimulation of production of white blood cells and platelets. Its potential use as a radiationcountermeasure was introduced by the Armed Forces Radiobiology Research Institute (AFRRI) and subsequently studied by AFRRI and Hollis-Eden Pharmaceuticals under the tradenameNeumune for the treatment of acute radiation syndrome.
Hollis-Eden had applied for a contract from the U.S. Government under the BioShield Request for Proposals (RFP) for radiation countermeasures. After being encouraged for 2.5 years that Neumune was in the competitive range, on March 9, 2007, the RFP was canceled by HHS. According to HHS, "the product was no longer in the competitive range".No further explanation was given. As a result, Hollis-Eden has now withdrawn from the radiation countermeasure field.
|Synonyms:||HERMAPHRODIOL;(3S,8R,9S,10R,13S,14S,17S)-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHRENE-3,17-DIOL;5-ANDROSTEN-3-BETA, 17-BETA-DIOL;5-ANDROSTENEDIOL;5-ANDROSTENEDIOL, 10,13-DIMETHYL-2,3,4,7,8,9,11,12,14,15,16,17-DODECAHYDRO-1H-CYCLOPENTA[A]PHENANTHRENE-3,17-DIOL;5-androstene-3b,17b-diol;5-ANDROSTENE-3BETA,17BETA-DIOL;ANDROSTENDIOL|
Δ5-Androstenediol (abbreviated as Δ5-diol), commonly referred to simply as androstenediol, and also known as androst-5-ene-3β,17β-dioland hermaphrodiol, is an endogenous androgen andestrogen steroid hormone and intermediate in thebiosynthesis of testosterone fromdehydroepiandrosterone (DHEA).
Δ5-Diol is a direct metabolite of the most abundant steroid produced by the human adrenal cortex, DHEA. It is less androgenic than the related compound, Δ4-androstenediol, and has been found to stimulate the immune system. When administered to rats, Δ5-diol, in vivo, has approximately 1.4% of the androgenicity of DHEA, 0.54% of the androgenicity of androstenedione, and 0.21% of the androgenicity of testosterone.
Δ5-Diol is a direct metabolite of the most abundant steroid produced by the human adrenal cortex. It is less androgenicthan the related compound, Δ4-androstenediol, and has been found to stimulate the immune system. When administered to rats, Δ5-diol, in vivo, has approximately 1.4% of the androgenicity of DHEA, 0.54% of the androgenicity of androstenedione, and 0.21% of the androgenicity of testosterone.
Δ5-Diol possesses potent estrogenic properties, similarly to DHEA and 3β-androstanediol.
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