|Place of Origin:||China|
|Minimum Order Quantity:||Free samples Available|
|Packaging Details:||Discreet package or as required|
|Delivery Time:||3-6 working days|
|Payment Terms:||T/T, Western Union, MoneyGram,BItcoins|
|Supply Ability:||500 kg / month|
|Grade:||Pharmaceutical Grade||Packing:||Discreet Ways Of Packing For Customs Pass Guaranteed|
pharmaceutical raw material,
raw materials for pharmaceutical products
SYN-AKE 823202-99-9 Pharmaceutical Intermediates White Powder Hair Loss Treatment Powder
CAS No.: 823202-99-9
Type: Vitamins, Amino Acids and Coenzymes
Product : SYN-AKE 823202-99-9
General name: SYN-AKE
INCI name: Dipeptide diaminobutyroyl benzylamide diacetate
Appearance: White dry-freezing powder
Molecular Formula: C19H29N5O3.2(C2H4O2)
Molecular Weight: 495.58
Application: Cosmetics (mask ,cream )
Water:not more than 10%
Acetic acid:not more than 15%
YScpAKE is a small peptide that simulates the activity of Waglerin I in snake venom toxin. Clinical trials have shown that snake venom can reduce wrinkles by suppressing muscle contraction and has excellent smooth and rapid wrinkle properties.
A new antiwrinkle active compound based on a synthetic tripeptide that mimics the effect of Waglerin 1,a peptide that is found in the venom of the Temple Viper, Tropidolaemus wagleri.
|Product Name:||(2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate|
|Synonyms:||(2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate;SYN-AKE;snake-tripeptide;H-β-Ala-Pro-Dab-NHBzl.2AcOH;Snake trippetide;Dipeptide Diaminobutyroyl Benzylamide Diacetate|
YScpAKE is a potent smooth and fouling active product that relaxes facial muscles and is consistent with the neuromuscular blockade compound Waglerin 1 of Temple Viper venom venom. YScpAKE (a snake-like tripeptide) acts on the postsynaptic membrane and is an antagonist of muscle nicotinic acetylcholine receptor (nmAChR) reversible. YScpAKE (serpentine tripeptide) binds to the? Subunit of nmAChR to block the binding of acetylcholine to the receptor, eventually leading to receptor closure, in the closed state of sodium can not be ingested, can not depolarize, nerve excitatory transmission block, The muscles are so loose.
The culture of cultured muscle cells showed that the use of 250 PPM YScpAKE (snake-like tripeptide) reduced muscle contraction by 36% after one minute and 82% after 2 hours, so snake venom could be used as an immediate wrinkle product.
YScpAKE (snake venom tripeptide) wrinkle determination:
Fifty subjects were involved in this study, and the YScpAKE (serotonin) was used in combination with placebo and reference substance. The trial lasted 28 days twice a day. The results showed that YScpAKE (serotonin tripeptide) significantly reduced the expression of the forehead, and the YScpAKE (serotonin) was significantly more active than the reference substance acetyl hexapeptide-8.
The raw material is a solution or a pure peptide
YScpAKE (serpentine tripeptide) solution
INCI Name: Water, Glycerin, Tripeptide
Appearance: transparent colorless to yellow viscous liquid
Content: 2000 ~ 3000ppm
PH: 4.5 to 5.5
Microbiological count: <100CFU / ml
Specific pathogens none
YScpAKE (serpentine tripeptide) pure peptide
Appearance: white crystal
Storage and shelf life
YScpAKE (venom-like tripeptide) solution must be stored in a cool, dark and clean place to ensure a shelf life of at least 12 months. Long-term storage, recommended storage at 4 ° C, shelf life can be extended to at least 18 months.
YScpAKE (serpentine tripeptide) pure peptide, recommended stored at 2-8 ° C, shelf life of 24 months.
In vitro and in vivo tests showed that the three peptides did not show any cytotoxicity, skin irritation, allergies and eye irritation
Application of liquid and recommended dosage:
Add cosmetic, such as lotions, gels, etc. in cosmetic formulations to achieve the desired effect of removing deep wrinkles or wrinkles around the forehead or eyes. Add 5% stock solution to the final stage of cosmetic production
Certificate of Analysis (COA) for SYN-AKE:
|CAS.NO.||823202-99-9||Sequence or Structure|
|Storage||Sealed, dry, avoid light preservation, 2-8℃.|
|Specification and certificate of Analysis|
|Appearance||White to yellowish Powder||Off-White Powder|
|PH(1％ Water Soln.)||3.0-6.0||5.35|
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